Development and Translation of Therapies for Spinal Muscular Atrophy

by Hannah K. Shorrock, Thomas H. Gillingwater
Published 2016-07-01

The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy

by James N. Sleigh, Thomas H. Gillingwater, Kevin Talbot
Published 2011-07-01

Molecular Mechanisms Underlying Sensory-Motor Circuit Dysfunction in SMA

by Hannah K. Shorrock, Hannah K. Shorrock, Thomas H. Gillingwater, Thomas H. Gillingwater, Ewout J. N. Groen, Ewout J. N. Groen
Published 2019-03-01

Synaptic protection in the brain of WldS mice occurs independently of age but is sensitive to gene-dose.

by Ann K Wright, Thomas M Wishart, Cali A Ingham, Thomas H Gillingwater
Published 2010-11-01

riboWaltz: Optimization of ribosome P-site positioning in ribosome profiling data.

by Fabio Lauria, Toma Tebaldi, Paola Bernabò, Ewout J N Groen, Thomas H Gillingwater, Gabriella Viero
Published 2018-08-01

Multi-Study Proteomic and Bioinformatic Identification of Molecular Overlap between Amyotrophic Lateral Sclerosis (ALS) and Spinal Muscular Atrophy (SMA)

by Darija Šoltić, Melissa Bowerman, Joanne Stock, Hannah K. Shorrock, Thomas H. Gillingwater, Heidi R. Fuller
Published 2018-12-01

Anatomical sciences at the University of Edinburgh: Initial experiences of teaching anatomy online

by Alethea H.C.M. Kelsey, Victoria McCulloch, Thomas H. Gillingwater, Gordon S. Findlater, Jennifer Z. Paxton
Published 2020-06-01

Morphological characteristics of motor neurons do not determine their relative susceptibility to degeneration in a mouse model of severe spinal muscular atrophy.

by Sophie R Thomson, Joya E Nahon, Chantal A Mutsaers, Derek Thomson, Gillian Hamilton, Simon H Parson, Thomas H Gillingwater
Published 2012-01-01

Total protein analysis as a reliable loading control for quantitative fluorescent Western blotting.

by Samantha L Eaton, Sarah L Roche, Maica Llavero Hurtado, Karla J Oldknow, Colin Farquharson, Thomas H Gillingwater, Thomas M Wishart
Published 2013-01-01

Induction of cell stress in neurons from transgenic mice expressing yellow fluorescent protein: implications for neurodegeneration research.

by Laura H Comley, Thomas M Wishart, Becki Baxter, Lyndsay M Murray, Ailish Nimmo, Derek Thomson, Simon H Parson, Thomas H Gillingwater
Published 2011-03-01

NMJ-morph reveals principal components of synaptic morphology influencing structure–function relationships at the neuromuscular junction

by Ross A. Jones, Caitlan D. Reich, Kosala N. Dissanayake, Fanney Kristmundsdottir, Gordon S. Findlater, Richard R. Ribchester, Martin W. Simmen, Thomas H. Gillingwater
Published 2016-01-01

Correction to ‘NMJ-morph reveals principal components of synaptic morphology influencing structure–function relationships at the neuromuscular junction’

by Ross A. Jones, Caitlan D. Reich, Kosala N. Dissanayake, Fanney Kristmundsdottir, Gordon S. Findlater, Richard R. Ribchester, Martin W. Simmen, Thomas H. Gillingwater
Published 2017-01-01

Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivo.

by Thomas M Wishart, Timothy M Rooney, Douglas J Lamont, Ann K Wright, A Jennifer Morton, Mandy Jackson, Marc R Freeman, Thomas H Gillingwater
Published 2012-01-01

Therapeutic strategies for spinal muscular atrophy: SMN and beyond

by Melissa Bowerman, Catherina G. Becker, Rafael J. Yáñez-Muñoz, Ke Ning, Matthew J. A. Wood, Thomas H. Gillingwater, Kevin Talbot, The UK SMA Research Consortium
Published 2017-08-01

Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy.

by Dirk Bäumer, Sheena Lee, George Nicholson, Joanna L Davies, Nicholas J Parkinson, Lyndsay M Murray, Thomas H Gillingwater, Olaf Ansorge, Kay E Davies, Kevin Talbot
Published 2009-12-01

Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture

by Laura C. Graham, Samantha L. Eaton, Paula J. Brunton, Abdelmadjid Atrih, Colin Smith, Douglas J. Lamont, Thomas H. Gillingwater, Giuseppa Pennetta, Paul Skehel, Thomas M. Wishart
Published 2017-10-01

aNMJ-morph: a simple macro for rapid analysis of neuromuscular junction morphology

by Gavin Minty, Alex Hoppen, Ines Boehm, Abrar Alhindi, Larissa Gibb, Ellie Potter, Boris C. Wagner, Janice Miller, Richard J. E. Skipworth, Thomas H. Gillingwater, Ross A. Jones
Published 2020-04-01

Immature Dentate Granule Cells Require Ntrk2/Trkb for the Formation of Functional Hippocampal Circuitry

by Sylvia Badurek, Marilena Griguoli, Aman Asif-Malik, Barbara Zonta, Fei Guo, Silvia Middei, Laura Lagostena, Maria Teresa Jurado-Parras, Thomas H. Gillingwater, Agnès Gruart, José María Delgado-García, Enrico Cherubini, Liliana Minichiello
Published 2020-05-01

Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction

by Emma M. Perkins, Karen Burr, Poulomi Banerjee, Arpan R. Mehta, Owen Dando, Bhuvaneish T. Selvaraj, Daumante Suminaite, Jyoti Nanda, Christopher M. Henstridge, Thomas H. Gillingwater, Giles E. Hardingham, David J. A. Wyllie, Siddharthan Chandran, Matthew R. Livesey
Published 2021-03-01

In Vivo Translatome Profiling in Spinal Muscular Atrophy Reveals a Role for SMN Protein in Ribosome Biology

by Paola Bernabò, Toma Tebaldi, Ewout J.N. Groen, Fiona M. Lane, Elena Perenthaler, Francesca Mattedi, Helen J. Newbery, Haiyan Zhou, Paola Zuccotti, Valentina Potrich, Hannah K. Shorrock, Francesco Muntoni, Alessandro Quattrone, Thomas H. Gillingwater, Gabriella Viero
Published 2017-10-01