KRAS and YAP1 Converge to Regulate EMT and Tumor Survival

by Shao, Diane D, Krall, Elsa B, Piccioni, Federica, Wang, Xiaoxing, Schinzel, Anna C, Rosenbluh, Joseph, Kim, Jong W, Zwang, Yaara, Roberts, Thomas M, Root, David E, Hahn, William C, Bhutkar, Arjun, Xue, Wen, Sood, Sabina, Jacks, Tyler E.
Published 2016

Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target

by Watanabe, Hideo, Francis, Joshua M., Woo, Michele S., Etemad, Banafsheh, Lin, Wenchu, Fries, Daniel F., Peng, Shouyong, Snyder, Eric, Tata, Purushothama Rao, Izzo, Francesca, Schinzel, Anna C., Cho, Jeonghee, Hammerman, Peter S., Verhaak, Roel G., Hahn, William C., Rajagopal, Jayaraj, Meyerson, Matthew L., Jacks, Tyler E
Published 2014

Synthetic Lethal Interaction between Oncogenic KRAS Dependency and STK33 Suppression in Human Cancer Cells

by Scholl, Claudia, Frohling, Stefan, Dunn, Ian F., Schinzel, Anna C., Barbie, David A., Kim, So Young, Silver, Serena J., Tamayo, Pablo, Wadlow, Raymond C., Ramaswamy, Sridhar, Dohner, Konstanze, Bullinger, Lars, Sandy, Peter, Boehm, Jesse S., Root, David E., Hahn, William C., Gilliland, D. Gary, Jacks, Tyler E
Published 2015

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

by Sandy, Peter, Meylan, Etienne, Reiling, Jan H., Hoersch, Sebastian, Barbie, David A., Tamayo, Pablo, Boehm, Jesse S., Kim, So Young, Moody, Susan E., Dunn, Ian F., Schinzel, Anna C., Scholl, Claudia, Frohling, Stefan, Chan, Edmond M., Sos, Martin L., Michel, Kathrin, Mermel, Craig H., Sabatini, David, Lander, Eric Steven, Jacks, Tyler E
Published 2014

Initial genome sequencing and analysis of multiple myeloma

by Chapman, Michael A., Lawrence, Michael S., Keats, Jonathan J., Cibulskis, Kristian, Sougnez, Carrie, Schinzel, Anna C., Harview, Christina L., Brunet, Jean-Philippe, Ahmann, Gregory J., Adli, Mazhar, Anderson, Kenneth C., Ardlie, Kristin, Auclair, Daniel, Baker, Angela, Bergsagel, P. Leif, Bernstein, Bradley E., Drier, Yotam, Fonseca, Rafael, Gabriel, Stacey B., Lander, Eric Steven
Published 2014

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

by Delmore, Jake E, Issa, Ghayas C, Lemieux, Madeleine E., Rahl, Peter B, Shi, Junwei, Jacobs, Hannah M, Kastritis, Efstathios, Gilpatrick, Timothy, Paranal, Ronald M, Qi, Jun, Chesi, Marta, Schinzel, Anna C, McKeown, Michael R, Heffernan, Timothy P., Vakoc, Christopher R, Bergsagel, P. Leif, Ghobrial, Irene M., Richardson, Paul G, Young, Richard A, Hahn, William C., Anderson, Kenneth C., Kung, Andrew L, Bradner, James E., Mitsiades, Constantine S.
Published 2014