The Polycomb Group Protein L3mbtl2 Assembles an Atypical PRC1-Family Complex that Is Essential in Pluripotent Stem Cells and Early Development

by Qin, Jinzhong, Whyte, Warren A, Anderssen, Endre, Apostolou, Effie, Chen, Hsu-Hsin, Akbarian, Schahram, Bronson, Roderick T., Hochedlinger, Konrad, Ramaswamy, Sridhar, Young, Richard A, Hock, Hanno, Young, Richard A., Whyte, Warren Anthony
Published 2014

MYC regulation of a "poor-prognosis" metastatic cancer cell state

by Mesirov, Jill P., Wolfer, Anita, Wittner, Ben S., Irimia, Daniel, Flavin, Richard J., Lupien, Mathieu, Gunawardane, Ruwanthi N., Meyer, Clifford A., Lightcap, Eric S., Tamayo, Pablo, Liu, X. Shirley, Shioda, Toshi, Toner, Mehmet, Loda, Massimo, Brown, Myles, Brugge, Joan S., Ramaswamy, Sridhar
Published 2014

Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism

by Perera, Rushika M., Stoykova, Svetlana, Nicolay, Brandon N., Ross, Kenneth N., Fitamant, Julien, Boukhali, Myriam, Lengrand, Justine, Deshpande, Vikram, Selig, Martin K., Ferrone, Cristina R., Settleman, Jeff, Stephanopoulos, Gregory, Dyson, Nicholas J., Zoncu, Roberto, Ramaswamy, Sridhar, Haas, Wilhelm, Bardeesy, Nabeel
Published 2017

Synthetic Lethal Interaction between Oncogenic KRAS Dependency and STK33 Suppression in Human Cancer Cells

by Scholl, Claudia, Frohling, Stefan, Dunn, Ian F., Schinzel, Anna C., Barbie, David A., Kim, So Young, Silver, Serena J., Tamayo, Pablo, Wadlow, Raymond C., Ramaswamy, Sridhar, Dohner, Konstanze, Bullinger, Lars, Sandy, Peter, Boehm, Jesse S., Root, David E., Hahn, William C., Gilliland, D. Gary, Jacks, Tyler E
Published 2015

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

by Kwiatkowski, Nicholas P., Zhang, Tinghu, Rahl, Peter B., Abraham, Brian J., Reddy, Jessica, Ficarro, Scott B., Dastur, Anahita, Amzallag, Arnaud, Ramaswamy, Sridhar, Tesar, Bethany, Jenkins, Catherine E., Hannett, Nancy M., McMillin, Douglas, Sanda, Takaomi, Sim, Taebo, Kim, Nam Doo, Look, A. Thomas, Mitsiades, Constantine S., Weng, Andrew P., Brown, Jennifer R., Benes, Cyril H., Marto, Jarrod A., Young, Richard A., Gray, Nathanael S.
Published 2015

Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer

by Faber, Anthony C., Costa, Carlotta, Dastur, Anahita, Gomez-Caraballo, Maria, Robbins, Rebecca, Wagner, Bethany L., Rideout, William M., Jakubik, Charles T., Ham, Jungoh, Edelman, Elena J., Ebi, Hiromichi, Yeo, Alan T., Hata, Aaron N., Song, Youngchul, Patel, Neha U., March, Ryan J., Tam, Ah Ting, Milano, Randy J., Boisvert, Jessica L., Hicks, Mark A., Elmiligy, Sarah, Malstrom, Scott E., Rivera, Miguel N., Harada, Hisashi, Windle, Brad E., Ramaswamy, Sridhar, Benes, Cyril H., Engelman, Jeffrey A., Farago, Anna, Malstrom, Scott E., Jacks, Tyler E
Published 2015