A protocol for rapid degradation of endogenous transcription factors in mammalian cells and identification of direct regulatory targets

by Hillary M. Layden, Nicholas A. Eleuteri, Scott W. Hiebert, Kristy R. Stengel
Published 2021-06-01

Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulation

by Jing Wang, Yue Zhao, Xiaofan Zhou, Scott W. Hiebert, Qi Liu, Yu Shyr
Published 2018-08-01

Human sterol 14α-demethylase as a target for anticancer chemotherapy: towards structure-aided drug design1

by Tatiana Y. Hargrove, Laura Friggeri, Zdzislaw Wawrzak, Suneethi Sivakumaran, Eugenia M. Yazlovitskaya, Scott W. Hiebert, F. Peter Guengerich, Michael R. Waterman, Galina I. Lepesheva
Published 2016-08-01

HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning

by Alessandra Ferrari, Raffaella Longo, Erika Fiorino, Rui Silva, Nico Mitro, Gaia Cermenati, Federica Gilardi, Béatrice Desvergne, Annapaola Andolfo, Cinzia Magagnotti, Donatella Caruso, Emma De Fabiani, Scott W. Hiebert, Maurizio Crestani
Published 2017-07-01

Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat.

by David F Razidlo, Tiffany J Whitney, Michelle E Casper, Meghan E McGee-Lawrence, Bridget A Stensgard, Xiaodong Li, Frank J Secreto, Sarah K Knutson, Scott W Hiebert, Jennifer J Westendorf
Published 2010-07-01

Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma.

by Christina E Wells, Srividya Bhaskara, Kristy R Stengel, Yue Zhao, Bianca Sirbu, Benjamin Chagot, David Cortez, Dineo Khabele, Walter J Chazin, Andrew Cooper, Vincent Jacques, James Rusche, Christine M Eischen, Laura Y McGirt, Scott W Hiebert
Published 2013-01-01

High-Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML

by Yue Zhao, Qi Liu, Pankaj Acharya, Kristy R. Stengel, Quanhu Sheng, Xiaofan Zhou, Hojoong Kwak, Melissa A. Fischer, James E. Bradner, Stephen A. Strickland, Sanjay R. Mohan, Michael R. Savona, Bryan J. Venters, Ming-Ming Zhou, John T. Lis, Scott W. Hiebert
Published 2016-08-01

Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters.

by Caitlyn W Barrett, J Joshua Smith, Lauren C Lu, Nicholas Markham, Kristy R Stengel, Sarah P Short, Sarah P Short, Baolin Zhang, Aubrey A Hunt, Barbara M Fingleton, Robert H Carnahan, Michael E Engel, Xi Chen, R Daniel Beauchamp, Keith T Wilson, Scott W Hiebert, Albert B Reynolds, Christopher S Williams
Published 2012-01-01

A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters

by Katerina Hatzi, Yanwen Jiang, Chuanxin Huang, Francine Garrett-Bakelman, Micah D. Gearhart, Eugenia G. Giannopoulou, Paul Zumbo, Kevin Kirouac, Srividya Bhaskara, Jose M. Polo, Matthias Kormaksson, Alexander D. MacKerell, Jr., Fengtian Xue, Christopher E. Mason, Scott W. Hiebert, Gilbert G. Prive, Leandro Cerchietti, Vivian J. Bardwell, Olivier Elemento, Ari Melnick
Published 2013-08-01

Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity

by Erin R. Aho, Jing Wang, Rocco D. Gogliotti, Gregory C. Howard, Jason Phan, Pankaj Acharya, Jonathan D. Macdonald, Ken Cheng, Shelly L. Lorey, Bin Lu, Sabine Wenzel, Audra M. Foshage, Joseph Alvarado, Feng Wang, J. Grace Shaw, Bin Zhao, April M. Weissmiller, Lance R. Thomas, Christopher R. Vakoc, Matthew D. Hall, Scott W. Hiebert, Qi Liu, Shaun R. Stauffer, Stephen W. Fesik, William P. Tansey
Published 2019-03-01

THE FUNCTIONS OF INHIBITOR OF DNA-BINDING PROTEINS IN ENDOTHELIAL CELLS DURING LUNG DEVELOPMENT AND DISEASE

by Zhang, Huimin
Published 2007