CNS reservoirs for HIV: implications for eradication

by Joanna Hellmuth, Victor Valcour, Serena Spudich
Published 2015-04-01

Compartmentalized human immunodeficiency virus type 1 originates from long-lived cells in some subjects with HIV-1-associated dementia.

by Gretja Schnell, Serena Spudich, Patrick Harrington, Richard W Price, Ronald Swanstrom
Published 2009-04-01

HIV-1 replication in the central nervous system occurs in two distinct cell types.

by Gretja Schnell, Sarah Joseph, Serena Spudich, Richard W Price, Ronald Swanstrom
Published 2011-10-01

Raltegravir cerebrospinal fluid concentrations in HIV-1 infection.

by Aylin Yilmaz, Magnus Gisslén, Serena Spudich, Evelyn Lee, Anura Jayewardene, Francesca Aweeka, Richard W Price
Published 2009-09-01

Compartmentalized replication of R5 T cell-tropic HIV-1 in the central nervous system early in the course of infection.

by Christa Buckheit Sturdevant, Sarah B Joseph, Gretja Schnell, Richard W Price, Ronald Swanstrom, Serena Spudich
Published 2015-03-01

Corrigendum to: “Plasma concentration of the neurofilament light protein (NFL) is a biomarker of CNS injury in HIV infection: A cross-sectional study” [EBioMedicine 3 (216) 135–140...

by Magnus Gisslén, Richard W. Price, Ulf Andreasson, Niklas Norgren, Staffan Nilsson, Lars Hagberg, Dietmar Fuchs, Serena Spudich, Kaj Blennow, Henrik Zetterberg
Published 2016-05-01

Plasma Concentration of the Neurofilament Light Protein (NFL) is a Biomarker of CNS Injury in HIV Infection: A Cross-Sectional Study

by Magnus Gisslén, Richard W. Price, Ulf Andreasson, Niklas Norgren, Staffan Nilsson, Lars Hagberg, Dietmar Fuchs, Serena Spudich, Kaj Blennow, Henrik Zetterberg
Published 2016-01-01

Safety of lumbar puncture procedure in an international research setting during acute HIV infection

by Phillip Chan, Joanna Hellmuth, Donn Colby, Eugene Kroon, Carlo Sacdalan, James Fletcher, Payal Patel, Suteera Pinyakorn, Victor Valcour, Jintanat Ananworanich, Serena Spudich
Published 2018-01-01

Neuropsychiatric outcomes before and after switching to dolutegravir-based therapy in an acute HIV cohort

by Phillip Chan, Orlanda Goh, Eugène Kroon, Donn Colby, Carlo Sacdalan, Suteeraporn Pinyakorn, Peeriya Prueksakaew, Peter Reiss, Jintanat Ananworanich, Victor Valcour, Serena Spudich, Robert Paul, the RV254/SEARCH 010 Research Team
Published 2020-01-01

Structural and functional brain imaging in acute HIV

by Vishal Samboju, Carissa L. Philippi, Phillip Chan, Yann Cobigo, James L.K. Fletcher, Merlin Robb, Joanna Hellmuth, Khunthalee Benjapornpong, Netsiri Dumrongpisutikul, Mantana Pothisri, Robert Paul, Jintanat Ananworanich, Serena Spudich, Victor Valcour
Published 2018-01-01

Compartmentalization of cerebrospinal fluid inflammation across the spectrum of untreated HIV-1 infection, central nervous system injury and viral suppression.

by Magnus Gisslen, Sheila M Keating, Serena Spudich, Victor Arechiga, Sophie Stephenson, Henrik Zetterberg, Clara Di Germanio, Kaj Blennow, Dietmar Fuchs, Lars Hagberg, Philip J Norris, Julia Peterson, Barbara L Shacklett, Constantin T Yiannoutsos, Richard W Price
Published 2021-01-01

Change in brain magnetic resonance spectroscopy after treatment during acute HIV infection.

by Napapon Sailasuta, William Ross, Jintanat Ananworanich, Thep Chalermchai, Victor DeGruttola, Sukalaya Lerdlum, Mantana Pothisri, Edgar Busovaca, Silvia Ratto-Kim, Linda Jagodzinski, Serena Spudich, Nelson Michael, Jerome H Kim, Victor Valcour, RV254/SEARCH 010 protocol teams
Published 2012-01-01

Predicting Efavirenz Concentrations in the Brain Tissue of HIV‐Infected Individuals and Exploring their Relationship to Neurocognitive Impairment

by Nithya Srinivas, Sarah Beth Joseph, Kevin Robertson, Laura P. Kincer, Prema Menezes, Lourdes Adamson, Amanda P. Schauer, Kimberly H. Blake, Nicole White, Craig Sykes, Paul Luciw, Joseph J. Eron, Alan Forrest, Richard W. Price, Serena Spudich, Ronald Swanstrom, Angela D.M. Kashuba
Published 2019-05-01

Prior Stroke and Age Predict Acute Ischemic Stroke Among Hospitalized COVID-19 Patients: A Derivation and Validation Study

by Teng J. Peng, Adam S. Jasne, Michael Simonov, Safa Abdelhakim, Gbambele Kone, Yee Kuang Cheng, Melissa Rethana, Karan Tarasaria, Alison L. Herman, Anna D. Baker, Shadi Yaghi, Shadi Yaghi, Jennifer A. Frontera, Lauren H. Sansing, Guido J. Falcone, Serena Spudich, Joseph Schindler, Kevin N. Sheth, Richa Sharma
Published 2021-10-01

Virological and immunological characteristics of HIV-infected individuals at the earliest stage of infection

by Jintanat Ananworanich, Carlo P. Sacdalan, Suteeraporn Pinyakorn, Nicolas Chomont, Mark Souza, de, Tassanee Luekasemsuk, Alexandra Schuetz, Shelly J. Krebs, Robin Dewar, Linda Jagodzinski, Sasiwimol Ubolyam, Rapee Trichavaroj, Sodsai Tovanabutra, Serena Spudich, Victor Valcour, Irini Sereti, Nelson Michael, Merlin Robb, Praphan Phanuphak, Jerome H. Kim, Nittaya Phanuphak
Published 2016-01-01

Acute encephalopathy with elevated CSF inflammatory markers as the initial presentation of COVID-19

by Shelli Farhadian, Laura R. Glick, Chantal B. F. Vogels, Jared Thomas, Jennifer Chiarella, Arnau Casanovas-Massana, Jing Zhou, Camila Odio, Pavithra Vijayakumar, Bertie Geng, John Fournier, Santos Bermejo, Joseph R. Fauver, Tara Alpert, Anne L. Wyllie, Cynthia Turcotte, Matthew Steinle, Patrick Paczkowski, Charles Dela Cruz, Craig Wilen, Albert I. Ko, Sean MacKay, Nathan D. Grubaugh, Serena Spudich, Lydia Aoun Barakat
Published 2020-06-01

A randomized trial of vorinostat with treatment interruption after initiating antiretroviral therapy during acute HIV-1 infection

by Eugène D.M.B. Kroon, Jintanat Ananworanich, Amélie Pagliuzza, Ajantha Rhodes, Nittaya Phanuphak, Lydie Trautmann, Julie L. Mitchell, Michelle Chintanaphol, Jintana Intasan, Suteeraporn Pinyakorn, Khuntalee Benjapornpong, J. Judy Chang, Donn J. Colby, Nitiya Chomchey, James L.K. Fletcher, Keith Eubanks, Hua Yang, John Kapson, Ashanti Dantanarayana, Surekha Tennakoon, Robert J. Gorelick, Frank Maldarelli, Merlin L. Robb, Jerome H. Kim, Serena Spudich, Nicolas Chomont, Praphan Phanuphak, Sharon R. Lewin, Mark S. de Souza
Published 2020-09-01

Deep Sequencing Reveals Central Nervous System Compartmentalization in Multiple Transmitted/Founder Virus Acute HIV-1 Infection

by Sodsai Tovanabutra, Rujipas Sirijatuphat, Phuc T. Pham, Lydia Bonar, Elizabeth A. Harbolick, Meera Bose, Hongshuo Song, David Chang, Celina Oropeza, Anne Marie O’Sullivan, Joyce Balinang, Eugene Kroon, Donn J. Colby, Carlo Sacdalan, Joanna Hellmuth, Phillip Chan, Peeriya Prueksakaew, Suteeraporn Pinyakorn, Linda L. Jagodzinski, Duanghathai Sutthichom, Suwanna Pattamaswin, Mark de Souza, Robert A. Gramzinski, Jerome H. Kim, Nelson L. Michael, Merlin L. Robb, Nittaya Phanuphak, Jintanat Ananworanich, Victor Valcour, Gustavo H. Kijak, Eric Sanders-Buell, Serena Spudich, The MHRP Viral Sequencing Core, the RV254/SEARCH 010 Study Team
Published 2019-08-01

Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms

by Eric Song, Christopher M. Bartley, Ryan D. Chow, Thomas T. Ngo, Ruoyi Jiang, Colin R. Zamecnik, Ravi Dandekar, Rita P. Loudermilk, Yile Dai, Feimei Liu, Sara Sunshine, Jamin Liu, Wesley Wu, Isobel A. Hawes, Bonny D. Alvarenga, Trung Huynh, Lindsay McAlpine, Nur-Taz Rahman, Bertie Geng, Jennifer Chiarella, Benjamin Goldman-Israelow, Chantal B.F. Vogels, Nathan D. Grubaugh, Arnau Casanovas-Massana, Brett S. Phinney, Michelle Salemi, Jessa R. Alexander, Juan A. Gallego, Todd Lencz, Hannah Walsh, Anne E. Wapniarski, Subhasis Mohanty, Carolina Lucas, Jon Klein, Tianyang Mao, Jieun Oh, Aaron Ring, Serena Spudich, Albert I. Ko, Steven H. Kleinstein, John Pak, Joseph L. DeRisi, Akiko Iwasaki, Samuel J. Pleasure, Michael R. Wilson, Shelli F. Farhadian
Published 2021-05-01