Transporters at the Interface between Cytosolic and Mitochondrial Amino Acid Metabolism

by Keeley G. Hewton, Amritpal S. Johal, Seth J. Parker
Published 2021-02-01

Distinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions

by Hui Zhang, Mehmet G. Badur, Ajit S. Divakaruni, Seth J. Parker, Christian Jäger, Karsten Hiller, Anne N. Murphy, Christian M. Metallo
Published 2016-08-01

Largazole and its derivatives selectively inhibit ubiquitin activating enzyme (e1).

by Dana Ungermannova, Seth J Parker, Christopher G Nasveschuk, Wei Wang, Bettina Quade, Gan Zhang, Robert D Kuchta, Andrew J Phillips, Xuedong Liu
Published 2012-01-01

Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer

by Kate E.R. Hollinshead, Seth J. Parker, Vinay V. Eapen, Joel Encarnacion-Rosado, Albert Sohn, Tugba Oncu, Michael Cammer, Joseph D. Mancias, Alec C. Kimmelman
Published 2020-10-01

Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Cells

by Mehmet G. Badur, Thangaselvam Muthusamy, Seth J. Parker, Shenghong Ma, Samuel K. McBrayer, Thekla Cordes, Jose H. Magana, Kun-Liang Guan, Christian M. Metallo
Published 2018-10-01

Spontaneous hydrolysis and spurious metabolic properties of α-ketoglutarate esters

by Seth J. Parker, Joel Encarnación-Rosado, Kate E. R. Hollinshead, David M. Hollinshead, Leonard J. Ash, Juan A. K. Rossi, Elaine Y. Lin, Albert S. W. Sohn, Mark R. Philips, Drew R. Jones, Alec C. Kimmelman
Published 2021-08-01

Disruption of redox homeostasis for combinatorial drug efficacy in K-Ras tumors as revealed by metabolic connectivity profiling

by Daniela Gaglio, Marcella Bonanomi, Silvia Valtorta, Rohit Bharat, Marilena Ripamonti, Federica Conte, Giulia Fiscon, Nicole Righi, Elisabetta Napodano, Federico Papa, Isabella Raccagni, Seth J. Parker, Ingrid Cifola, Tania Camboni, Paola Paci, Anna Maria Colangelo, Marco Vanoni, Christian M. Metallo, Rosa Maria Moresco, Lilia Alberghina
Published 2020-09-01