Biomarkers for Immune Checkpoint Inhibitors in Melanoma

by Shigehisa Kitano, Shigehisa Kitano, Takayuki Nakayama, Makiko Yamashita
Published 2018-07-01

Clinical Development of Immune Checkpoint Inhibitors

by Ayumu Ito, Shunsuke Kondo, Kohei Tada, Shigehisa Kitano
Published 2015-01-01

Severe colitis after PD-1 blockade with nivolumab in advanced melanoma patients: potential role of Th1-dominant immune response in immune-related adverse events: two case reports

by Koji Yoshino, Takayuki Nakayama, Ayumu Ito, Eiichi Sato, Shigehisa Kitano
Published 2019-10-01

Enhancement of antitumor effect by peptide vaccine therapy in combination with anti-CD4 antibody: Study in a murine model

by Norihiro Fujinami, Toshiaki Yoshikawa, Yu Sawada, Manami Shimomura, Tatsuaki Iwama, Shiori Sugai, Shigehisa Kitano, Yasushi Uemura, Tetsuya Nakatsura
Published 2016-03-01

Complete Pathological Response to Neoadjuvant Pembrolizumab in a Patient With Chemoresistant Upper Urinary Tract Urothelial Carcinoma: A Case Report

by Daiki Ikarashi, Daiki Ikarashi, Daiki Ikarashi, Shigehisa Kitano, Kazuyuki Ishida, Tetsuya Nakatsura, Hitoshi Shimodate, Takashi Tsuyukubo, Daichi Tamura, Renpei Kato, Tamotsu Sugai, Wataru Obara
Published 2020-09-01

Case Report: A Case of Trimethoprim/Sulfamethoxazole-Triggered Hypotensive Shock: Cytokine Release Syndrome Related to Immune Checkpoint Inhibitors and Drug-Induced Hypersensitivit...

by Tetsuya Urasaki, Makiko Ono, Toshiaki Mochizuki, Koichi Takeda, Aya Nishizawa, Eri Fukagawa, Motohiro Fujiwara, Yoshinobu Komai, Shigehisa Kitano, Takeshi Yuasa, Junji Yonese, Shunji Takahashi
Published 2021-04-01

Serial pseudoprogression of metastatic malignant melanoma in a patient treated with nivolumab: a case report

by Yukinori Ozaki, Junichi Shindoh, Yuji Miura, Hiromichi Nakajima, Ryosuke Oki, Miyuki Uchiyama, Jun Masuda, Keiichi Kinowaki, Chihiro Kondoh, Yuko Tanabe, Tsuyoshi Tanaka, Shusuke Haruta, Masaki Ueno, Shigehisa Kitano, Takeshi Fujii, Harushi Udagawa, Toshimi Takano
Published 2017-11-01

Chimeric Antigen Receptor T-Cells for the Treatment of B-Cell Acute Lymphoblastic Leukemia

by Ciprian Tomuleasa, Ciprian Tomuleasa, Shigeo Fuji, Cristian Berce, Anca Onaciu, Sergiu Chira, Bobe Petrushev, Wilhelm-Thomas Micu, Vlad Moisoiu, Ciprian Osan, Catalin Constantinescu, Sergiu Pasca, Ancuta Jurj, Laura Pop, Ioana Berindan-Neagoe, Delia Dima, Shigehisa Kitano
Published 2018-02-01

First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors

by Kohei Shitara, Satoshi Ueha, Shigeyuki Shichino, Hiroyasu Aoki, Haru Ogiwara, Tetsuya Nakatsura, Toshihiro Suzuki, Manami Shimomura, Toshiaki Yoshikawa, Kayoko Shoda, Shigehisa Kitano, Makiko Yamashita, Takayuki Nakayama, Akihiro Sato, Sakiko Kuroda, Masashi Wakabayashi, Shogo Nomura, Shoji Yokochi, Satoru Ito, Kouji Matsushima, Toshihiko Doi
Published 2019-07-01

Discovery of a Good Responder Subtype of Esophageal Squamous Cell Carcinoma with Cytotoxic T-Lymphocyte Signatures Activated by Chemoradiotherapy.

by Yosuke Tanaka, Kazuhiko Aoyagi, Keiko Minashi, Rie Komatsuzaki, Masayuki Komatsu, Fumiko Chiwaki, Masashi Tamaoki, Takao Nishimura, Naoki Takahashi, Ichiro Oda, Yuji Tachimori, Tokuzo Arao, Kazuto Nishio, Shigehisa Kitano, Kenta Narumi, Kazunori Aoki, Satoshi Fujii, Atsushi Ochiai, Teruhiko Yoshida, Manabu Muto, Yasuhide Yamada, Hiroki Sasaki
Published 2015-01-01

Comparison of Tumor Microenvironments Between Primary Tumors and Brain Metastases in Patients With NSCLC

by Daiki Ikarashi, MD, PhD, Tamio Okimoto, MD, PhD, Takehito Shukuya, MD, PhD, Hiroko Onagi, MD, Takuo Hayashi, MD, PhD, Sara L. Sinicropi-Yao, PhD, Joseph M. Amann, PhD, Tetsuya Nakatsura, MD, PhD, Shigehisa Kitano, MD, PhD, David P. Carbone, MD, PhD
Published 2021-10-01

Approach to the Adult Acute Lymphoblastic Leukemia Patient

by Valentina Sas, Vlad Moisoiu, Patric Teodorescu, Sebastian Tranca, Laura Pop, Sabina Iluta, Sergiu Pasca, Cristina Blag, Sorin Man, Andrei Roman, Catalin Constantinescu, Ioana Rus, Mihail Buse, Bogdan Fetica, Mirela Marian, Cristina Selicean, Ioana Berindan-Neagoe, Bobe Petrushev, Horia Bumbea, Alina Tanase, Mihnea Zdrenghea, Shigeo Fuji, Shigehisa Kitano, Ciprian Tomuleasa, Romanian-Japanese Working Group of the Romanian Society for Bone Marrow Transplantation
Published 2019-08-01