Potential therapeutic applications for interleukin 1: anti-tumor and hematopoietic effects

by Joost J. Oppenheeim, Kouji Matsushima, Kikuo Onozaki, Ruth Neta
Published 1987-01-01

Mesenchymal-Epithelial Interactome Analysis Reveals Essential Factors Required for Fibroblast-Free Alveolosphere Formation

by Kazushige Shiraishi, Shigeyuki Shichino, Satoshi Ueha, Takuya Nakajima, Shinichi Hashimoto, Satoshi Yamazaki, Kouji Matsushima
Published 2019-01-01

Reduction of Proliferating Olfactory Cells and Low Expression of Extracellular Matrix Genes Are Hallmarks of the Aged Olfactory Mucosa

by Rumi Ueha, Shigeyuki Shichino, Satoshi Ueha, Kenji Kondo, Shu Kikuta, Hironobu Nishijima, Kouji Matsushima, Tatsuya Yamasoba
Published 2018-03-01

The Effect of Suplatast Tosilate on TARC Production in Peripheral Blood Mononuclear Cells and TARC Plasma Levels

by Shigeki Gorai, Nobuhisa Terada, Tadashi Kobayashi, Tomohiro Nomura, Woo Jeong Kim, Nobuyuki Onai, Kouji Matsushima, Akiyoshi Konno
Published 2005-01-01

TCR Repertoire Analysis Reveals Mobilization of Novel CD8+ T Cell Clones Into the Cancer-Immunity Cycle Following Anti-CD4 Antibody Administration

by Hiroyasu Aoki, Hiroyasu Aoki, Satoshi Ueha, Satoshi Ueha, Shigeyuki Shichino, Shigeyuki Shichino, Haru Ogiwara, Haru Ogiwara, Shin-ichi Hashimoto, Shin-ichi Hashimoto, Shin-ichi Hashimoto, Kazuhiro Kakimi, Satoru Ito, Satoru Ito, Satoru Ito, Kouji Matsushima, Kouji Matsushima
Published 2019-01-01

Novel Targeting to XCR1+ Dendritic Cells Using Allogeneic T Cells for Polytopical Antibody Responses in the Lymph Nodes

by Yusuke Kitazawa, Hisashi Ueta, Yasushi Sawanobori, Tomoya Katakai, Hiroyuki Yoneyama, Satoshi Ueha, Kouji Matsushima, Nobuko Tokuda, Kenjiro Matsuno
Published 2019-05-01

Heat Shock Protein 27 Plays a Pivotal Role in Myofibroblast Differentiation and in the Development of Bleomycin-Induced Pulmonary Fibrosis.

by Ah-Mee Park, Kyosuke Kanai, Tatsuki Itoh, Takao Sato, Tatsuya Tsukui, Yutaka Inagaki, Moises Selman, Kouji Matsushima, Osamu Yoshie
Published 2016-01-01

Choroidal Neovascularization Is Inhibited in Splenic-Denervated or Splenectomized Mice with a Concomitant Decrease in Intraocular Macrophage.

by Xue Tan, Katsuhito Fujiu, Ichiro Manabe, Junko Nishida, Reiko Yamagishi, Yuya Terashima, Kouji Matsushima, Toshikatsu Kaburaki, Ryozo Nagai, Yasuo Yanagi
Published 2016-01-01

The HIV co-receptor CCR5 regulates osteoclast function

by Ji-Won Lee, Akiyoshi Hoshino, Kazuki Inoue, Takashi Saitou, Shunsuke Uehara, Yasuhiro Kobayashi, Satoshi Ueha, Kouji Matsushima, Akira Yamaguchi, Yuuki Imai, Tadahiro Iimura
Published 2017-12-01

Fas Ligand Has a Greater Impact than TNF-α on Apoptosis and Inflammation in Ischemic Acute Kidney Injury

by Kengo Furuichi, Satoshi Kokubo, Akinori Hara, Ryu Imamura, Qiang Wang, Shinji Kitajima, Tadashi Toyama, Toshiya Okumura, Kouji Matsushima, Takashi Suda, Naofumi Mukaida, Shuichi Kaneko, Takashi Wada
Published 2012-02-01

Combined treatment with HMGN1 and anti-CD4 depleting antibody reverses T cell exhaustion and exerts robust anti-tumor effects in mice

by Chang-Yu Chen, Satoshi Ueha, Yoshiro Ishiwata, Shoji Yokochi, De Yang, Joost J. Oppenheim, Haru Ogiwara, Shigeyuki Shichino, Shungo Deshimaru, Francis H. W. Shand, Shiro Shibayama, Kouji Matsushima
Published 2019-01-01

A Combination of Mitochondrial Oxidative Stress and Excess Fat/Calorie Intake Accelerates Steatohepatitis by Enhancing Hepatic CC Chemokine Production in Mice.

by Tadashi Moro, Sachie Nakao, Hideaki Sumiyoshi, Takamasa Ishii, Masaki Miyazawa, Naoaki Ishii, Tadayuki Sato, Yumi Iida, Yoshinori Okada, Masayuki Tanaka, Hideki Hayashi, Satoshi Ueha, Kouji Matsushima, Yutaka Inagaki
Published 2016-01-01

Long-Lasting Graft-Derived Donor T Cells Contribute to the Pathogenesis of Chronic Graft-versus-Host Disease in Mice

by Mizuha Kosugi-Kanaya, Mizuha Kosugi-Kanaya, Mizuha Kosugi-Kanaya, Satoshi Ueha, Satoshi Ueha, Jun Abe, Jun Abe, Shigeyuki Shichino, Shigeyuki Shichino, Francis H. W. Shand, Francis H. W. Shand, Teppei Morikawa, Makoto Kurachi, Yusuke Shono, Naoto Sudo, Naoto Sudo, Ai Yamashita, Ai Yamashita, Fumiko Suenaga, Fumiko Suenaga, Akihiro Yokoyama, Akihiro Yokoyama, Wang Yong, Wang Yong, Masahiro Imamura, Takanori Teshima, Kouji Matsushima, Kouji Matsushima
Published 2017-12-01

DOCK11 and DENND2A play pivotal roles in the maintenance of hepatitis B virus in host cells.

by Shinichi Hashimoto, Takayoshi Shirasaki, Taro Yamashita, Sadahiro Iwabuchi, Yutaka Suzuki, Yuzuru Takamura, Yoshiaki Ukita, Shungo Deshimaru, Toshitugu Okayama, Kazuho Ikeo, Kazuyuki Kuroki, Kazunori Kawaguchi, Eishiro Mizukoshi, Kouji Matsushima, Masao Honda, Shuichi Kaneko
Published 2021-01-01

Immunization with a recombinant vaccinia virus that encodes nonstructural proteins of the hepatitis C virus suppresses viral protein levels in mouse liver.

by Satoshi Sekiguchi, Kiminori Kimura, Tomoko Chiyo, Takahiro Ohtsuki, Yoshimi Tobita, Yuko Tokunaga, Fumihiko Yasui, Kyoko Tsukiyama-Kohara, Takaji Wakita, Toshiyuki Tanaka, Masayuki Miyasaka, Kyosuke Mizuno, Yukiko Hayashi, Tsunekazu Hishima, Kouji Matsushima, Michinori Kohara
Published 2012-01-01

High-resolution analysis of the 5'-end transcriptome using a next generation DNA sequencer.

by Shin-ichi Hashimoto, Wei Qu, Budrul Ahsan, Katsumi Ogoshi, Atsushi Sasaki, Yoichiro Nakatani, Yongjun Lee, Masako Ogawa, Akio Ametani, Yutaka Suzuki, Sumio Sugano, Clarence C Lee, Robert C Nutter, Shinichi Morishita, Kouji Matsushima
Published 2009-01-01

First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors

by Kohei Shitara, Satoshi Ueha, Shigeyuki Shichino, Hiroyasu Aoki, Haru Ogiwara, Tetsuya Nakatsura, Toshihiro Suzuki, Manami Shimomura, Toshiaki Yoshikawa, Kayoko Shoda, Shigehisa Kitano, Makiko Yamashita, Takayuki Nakayama, Akihiro Sato, Sakiko Kuroda, Masashi Wakabayashi, Shogo Nomura, Shoji Yokochi, Satoru Ito, Kouji Matsushima, Toshihiko Doi
Published 2019-07-01

Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer

by Takashi Nishina, Yutaka Deguchi, Daisuke Ohshima, Wakami Takeda, Masato Ohtsuka, Shigeyuki Shichino, Satoshi Ueha, Soh Yamazaki, Mika Kawauchi, Eri Nakamura, Chiharu Nishiyama, Yuko Kojima, Satomi Adachi-Akahane, Mizuho Hasegawa, Mizuho Nakayama, Masanobu Oshima, Hideo Yagita, Kazutoshi Shibuya, Tetuo Mikami, Naohiro Inohara, Kouji Matsushima, Norihiro Tada, Hiroyasu Nakano
Published 2021-04-01

Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties

by Yuya Terashima, Etsuko Toda, Meiji Itakura, Mikiya Otsuji, Sosuke Yoshinaga, Kazuhiro Okumura, Francis H. W. Shand, Yoshihiro Komohara, Mitsuhiro Takeda, Kana Kokubo, Ming-Chen Chen, Sana Yokoi, Hirofumi Rokutan, Yutaka Kofuku, Koji Ohnishi, Miki Ohira, Toshihiko Iizasa, Hirofumi Nakano, Takayoshi Okabe, Hirotatsu Kojima, Akira Shimizu, Shiro Kanegasaki, Ming-Rong Zhang, Ichio Shimada, Hiroki Nagase, Hiroaki Terasawa, Kouji Matsushima
Published 2020-01-01

Bovine Induced Pluripotent Stem Cells Are More Resistant to Apoptosis than Testicular Cells in Response to Mono-(2-ethylhexyl) Phthalate

by Ying-Chu Lin, Kung-Kai Kuo, Kenly Wuputra, Shih-Han Lin, Chia-Chen Ku, Ya-Han Yang, Shin-Wei Wang, Sheng-Wen Wang, Deng-Chyang Wu, Chun-Chien Wu, Chee-Yin Chai, Cheng-Lung Lin, Chang-Shen Lin, Masayuki Kajitani, Hiroyuki Miyoshi, Yukio Nakamura, Shinichi Hashimoto, Kouji Matsushima, Chunyuan Jin, Shau-Ku Huang, Shigeo Saito, Kazunari K. Yokoyama
Published 2014-03-01