Brain Hypothermic Therapy Dramatically Decreases Elevated Blood Concentrations of High Mobility Group Box 1 in Neonates with Hypoxic-Ischemic Encephalopathy

by Toshihiko Nakamura, Shingo Yamada, Toshirou Yoshioka
Published 2013-01-01

The Ratio of Oxidized Lipoprotein(a) to Native Lipoprotein(a) and the Endothelial Function in Patients with Type 2 Diabetes Mellitus

by Kazuhiko Kotani, Shingo Yamada, Hirokazu Takahashi, Yoshitaka Iwazu, Toshiyuki Yamada
Published 2019-10-01

Specific detection of high mobility group box 1 degradation product with a novel ELISA

by Takaaki Totoki, Takashi Ito, Shingo Yamada, Goichi Honda, Tsuyoshi Hattori, Ikuro Maruyama
Published 2021-06-01

Differential Regulation of Damage-Associated Molecular Pattern Release in a Mouse Model of Skeletal Muscle Ischemia/Reperfusion Injury

by Hiroaki Furubeppu, Takashi Ito, Midori Kakuuchi, Tomotsugu Yasuda, Chinatsu Kamikokuryo, Shingo Yamada, Ikuro Maruyama, Yasuyuki Kakihana
Published 2021-07-01

Serum histone H3 levels and platelet counts are potential markers for coagulopathy with high risk of death in septic patients: a single-center observational study

by Takashi Ito, Takaaki Totoki, Yayoi Yokoyama, Tomotsugu Yasuda, Hiroaki Furubeppu, Shingo Yamada, Ikuro Maruyama, Yasuyuki Kakihana
Published 2019-12-01

Circulating histone H3 levels in septic patients are associated with coagulopathy, multiple organ failure, and death: a single-center observational study

by Yayoi Yokoyama, Takashi Ito, Tomotsugu Yasuda, Hiroaki Furubeppu, Chinatsu Kamikokuryo, Shingo Yamada, Ikuro Maruyama, Yasuyuki Kakihana
Published 2019-01-01

Circulating Syndecan-1 as a Predictor of Persistent Thrombocytopenia and Lethal Outcome: A Population Study of Patients With Suspected Sepsis Requiring Intensive Care

by Kosaku Hatanaka, Takashi Ito, Yutaro Madokoro, Chinatsu Kamikokuryo, Shuhei Niiyama, Shingo Yamada, Ikuro Maruyama, Yasuyuki Kakihana
Published 2021-09-01

HMGB1 promotes the development of pulmonary arterial hypertension in rats.

by Yukari Sadamura-Takenaka, Takashi Ito, Satoshi Noma, Yoko Oyama, Shingo Yamada, Ko-ichi Kawahara, Hiromasa Inoue, Ikuro Maruyama
Published 2014-01-01

Total and high molecular weight adiponectin and hepatocellular carcinoma with HCV infection.

by Shuji Sumie, Takumi Kawaguchi, Ryoko Kuromatsu, Akio Takata, Masahito Nakano, Manabu Satani, Shingo Yamada, Takashi Niizeki, Takuji Torimura, Michio Sata
Published 2011-01-01

Circulating histone H3 levels are increased in septic mice in a neutrophil-dependent manner: preclinical evaluation of a novel sandwich ELISA for histone H3

by Takashi Ito, Mayumi Nakahara, Yoshiki Masuda, Sachie Ono, Shingo Yamada, Hiroyasu Ishikura, Hitoshi Imaizumi, Chinatsu Kamikokuryo, Yasuyuki Kakihana, Ikuro Maruyama
Published 2018-11-01

Gradual Increase of High Mobility Group Protein B1 in the Lungs after the Onset of Acute Exacerbation of Idiopathic Pulmonary Fibrosis

by Masahito Ebina, Hiroyuki Taniguchi, Taku Miyasho, Shingo Yamada, Naoko Shibata, Hiromitsu Ohta, Shu Hisata, Shinya Ohkouchi, Tsutomu Tamada, Hidekazu Nishimura, Akitoshi Ishizaka, Ikuro Maruyama, Yoshinori Okada, Kondo Takashi, Toshihiro Nukiwa
Published 2011-01-01

Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism.

by Mayumi Nakahara, Takashi Ito, Ko-ichi Kawahara, Mika Yamamoto, Tomoka Nagasato, Binita Shrestha, Shingo Yamada, Takahiro Miyauchi, Koji Higuchi, Toshihiro Takenaka, Tomotsugu Yasuda, Akira Matsunaga, Yasuyuki Kakihana, Teruto Hashiguchi, Yuichi Kanmura, Ikuro Maruyama
Published 2013-01-01

YAP-dependent necrosis occurs in early stages of Alzheimer’s disease and regulates mouse model pathology

by Hikari Tanaka, Hidenori Homma, Kyota Fujita, Kanoh Kondo, Shingo Yamada, Xiaocen Jin, Masaaki Waragai, Gaku Ohtomo, Atsushi Iwata, Kazuhiko Tagawa, Naoki Atsuta, Masahisa Katsuno, Naoki Tomita, Katsutoshi Furukawa, Yuko Saito, Takashi Saito, Ayaka Ichise, Shinsuke Shibata, Hiroyuki Arai, Takaomi Saido, Marius Sudol, Shin-ichi Muramatsu, Hideyuki Okano, Elliott J. Mufson, Gen Sobue, Shigeo Murayama, Hitoshi Okazawa
Published 2020-01-01