Acrolein Is a Pathogenic Mediator of Alcoholic Liver Disease and the Scavenger Hydralazine Is Protective in MiceSummary

by Wei-Yang Chen, Jingwen Zhang, Smita Ghare, Shirish Barve, Craig McClain, Swati Joshi-Barve
Published 2016-09-01

Perturbation of Methionine/S-adenosylmethionine Metabolism as a Novel Vulnerability in MLL Rearranged Leukemia

by Aditya Barve, Alexis Vega, Parag P. Shah, Smita Ghare, Lavona Casson, Mark Wunderlich, Leah J. Siskind, Levi J. Beverly
Published 2019-10-01

Tributyrin Inhibits Ethanol-Induced Epigenetic Repression of CPT-1A and Attenuates Hepatic Steatosis and InjurySummary

by Hridgandh Donde, Smita Ghare, Swati Joshi-Barve, JingWen Zhang, Manicka V. Vadhanam, Leila Gobejishvili, Pawel Lorkiewicz, Sanjay Srivastava, Craig J. McClain, Shirish Barve
Published 2020-01-01

Decrease in acetyl-CoA pathway utilizing butyrate-producing bacteria is a key pathogenic feature of alcohol-induced functional gut microbial dysbiosis and development of liver dise...

by Richa Singhal, Hridgandh Donde, Smita Ghare, Kendall Stocke, Jingwein Zhang, Manicka Vadhanam, Sreelatha Reddy, Leila Gobejishvili, Paula Chilton, Swati Joshi-Barve, Wenke Feng, Craig McClain, Kristi Hoffman, Joseph Petrosino, Marius Vital, Shirish Barve
Published 2021-01-01

A specific low-density neutrophil population correlates with hypercoagulation and disease severity in hospitalized COVID-19 patients

by Samantha M. Morrissey, Anne E. Geller, Xiaoling Hu, David Tieri, Chuanlin Ding, Christopher K. Klaes, Elizabeth A. Cooke, Matthew R. Woeste, Zachary C. Martin, Oscar Chen, Sarah E. Bush, Huang-ge Zhang, Rodrigo Cavallazzi, Sean P. Clifford, James Chen, Smita Ghare, Shirish S. Barve, Lu Cai, Maiying Kong, Eric C. Rouchka, Kenneth R. McLeish, Silvia M. Uriarte, Corey T. Watson, Jiapeng Huang, Jun Yan
Published 2021-05-01