Opioid-Induced Immunomodulation: Consequences for the Experimental Coxsackievirus B3-Induced Myocarditis Model

by Kathleen Pappritz, Sophie Van Linthout
Published 2020-10-01

Epicardial Fat Expansion in Diabetic and Obese Patients With Heart Failure and Preserved Ejection Fraction—A Specific HFpEF Phenotype

by Ahmed Elsanhoury, Ahmed Elsanhoury, Vivian Nelki, Sebastian Kelle, Sophie Van Linthout, Sophie Van Linthout, Carsten Tschöpe, Carsten Tschöpe, Carsten Tschöpe
Published 2021-09-01

Immunomodulatory Effects of Mesenchymal Stromal Cells Revisited in the Context of Inflammatory Cardiomyopathy

by Kapka Miteva, Sophie Van Linthout, Hans-Dieter Volk, Carsten Tschöpe
Published 2013-01-01

Extracellular vesicles from regenerative human cardiac cells act as potent immune modulators by priming monocytes

by Christien M. Beez, Marion Haag, Oliver Klein, Sophie Van Linthout, Michael Sittinger, Martina Seifert
Published 2019-05-01

Mechanobiological Principles Influence the Immune Response in Regeneration: Implications for Bone Healing

by Raphael S. Knecht, Christian H. Bucher, Christian H. Bucher, Sophie Van Linthout, Sophie Van Linthout, Carsten Tschöpe, Carsten Tschöpe, Carsten Tschöpe, Katharina Schmidt-Bleek, Katharina Schmidt-Bleek, Georg N. Duda, Georg N. Duda
Published 2021-02-01

Myeloid-Derived Suppressor Cells Restrain Natural Killer Cell Activity in Acute Coxsackievirus B3-Induced Myocarditis

by Irene Müller, Lisa Janson, Martina Sauter, Kathleen Pappritz, Sophie Van Linthout, Carsten Tschöpe, Karin Klingel
Published 2021-05-01

Impact of Syndecan-2-Selected Mesenchymal Stromal Cells on the Early Onset of Diabetic Cardiomyopathy in Diabetic db/db Mice

by Kathleen Pappritz, Kathleen Pappritz, Kathleen Pappritz, Fengquan Dong, Kapka Miteva, Kapka Miteva, Arpad Kovacs, Muhammad El-Shafeey, Muhammad El-Shafeey, Muhammad El-Shafeey, Muhammad El-Shafeey, Bahtiyar Kerim, Lisa O'Flynn, Stephen Joseph Elliman, Timothy O'Brien, Nazha Hamdani, Nazha Hamdani, Nazha Hamdani, Carsten Tschöpe, Carsten Tschöpe, Carsten Tschöpe, Carsten Tschöpe, Sophie Van Linthout, Sophie Van Linthout, Sophie Van Linthout
Published 2021-05-01

Serum alarmin S100A8/S100A9 levels and its potential role as biomarker in myocarditis

by Irene Müller, Thomas Vogl, Uwe Kühl, Alexander Krannich, Aron Banks, Tobias Trippel, Michel Noutsias, Alan S. Maisel, Sophie vanLinthout, Carsten Tschöpe
Published 2020-08-01

Cardiac Migration of Endogenous Mesenchymal Stromal Cells in Patients with Inflammatory Cardiomyopathy

by Caroline Schmidt-Lucke, Felicitas Escher, Sophie Van Linthout, Uwe Kühl, Kapka Miteva, Jochen Ringe, Thomas Zobel, Heinz-Peter Schultheiss, Carsten Tschöpe
Published 2015-01-01

Mesenchymal stromal cells inhibit NLRP3 inflammasome activation in a model of Coxsackievirus B3-induced inflammatory cardiomyopathy

by Kapka Miteva, Kathleen Pappritz, Marzena Sosnowski, Muhammad El-Shafeey, Irene Müller, Fengquan Dong, Konstantinos Savvatis, Jochen Ringe, Carsten Tschöpe, Sophie Van Linthout
Published 2018-02-01

Toll-Like Receptors: Are They Taking a Toll on the Heart in Viral Myocarditis?

by Kasper Favere, Matthias Bosman, Karin Klingel, Stephane Heymans, Sophie Van Linthout, Peter L. Delputte, Johan De Sutter, Hein Heidbuchel, Pieter-Jan Guns
Published 2021-05-01

Human cardiac-derived adherent proliferating cells reduce murine acute Coxsackievirus B3-induced myocarditis.

by Kapka Miteva, Marion Haag, Jun Peng, Kostas Savvatis, Peter Moritz Becher, Martina Seifert, Katrin Warstat, Dirk Westermann, Jochen Ringe, Michael Sittinger, Heinz-Peter Schultheiss, Carsten Tschöpe, Sophie Van Linthout
Published 2011-01-01

Modulation of the acute defence reaction by eplerenone prevents cardiac disease progression in viral myocarditis

by Carsten Tschöpe, Sophie Van Linthout, Sebastian Jäger, Robert Arndt, Tobias Trippel, Irene Müller, Ahmed Elsanhoury, Susanne Rutschow, Stefan D. Anker, Heinz‐Peter Schultheiss, Matthias Pauschinger, Frank Spillmann, Kathleen Pappritz
Published 2020-10-01

CX3CR1 knockout aggravates Coxsackievirus B3-induced myocarditis.

by Irene Müller, Kathleen Pappritz, Konstantinos Savvatis, Kerstin Puhl, Fengquan Dong, Muhammad El-Shafeey, Nazha Hamdani, Isabell Hamann, Michel Noutsias, Carmen Infante-Duarte, Wolfgang A Linke, Sophie Van Linthout, Carsten Tschöpe
Published 2017-01-01

Mesenchymal stromal cells but not cardiac fibroblasts exert beneficial systemic immunomodulatory effects in experimental myocarditis.

by Konstantinos Savvatis, Sophie van Linthout, Kapka Miteva, Kathleen Pappritz, Dirk Westermann, Joerg C Schefold, Gerhard Fusch, Alice Weithäuser, Ursula Rauch, Peter-Moritz Becher, Karin Klingel, Jochen Ringe, Andreas Kurtz, Heinz-Peter Schultheiss, Carsten Tschöpe
Published 2012-01-01

Accurate assessment of LV function using the first automated 2D-border detection algorithm for small animals - evaluation and application to models of LV dysfunction

by Jana Grune, Daniel Ritter, Kristin Kräker, Kathleen Pappritz, Niklas Beyhoff, Till Schütte, Christiane Ott, Cathleen John, Sophie van Linthout, Carsten Tschöpe, Ralf Dechend, Dominik N. Muller, Nadine Haase, Tilman Grune, Ulrich Kintscher, Wolfgang M. Kuebler
Published 2019-04-01

Interventricular Differences of Signaling Pathways-Mediated Regulation of Cardiomyocyte Function in Response to High Oxidative Stress in the Post-Ischemic Failing Rat Heart

by Árpád Kovács, Melissa Herwig, Heidi Budde, Simin Delalat, Detmar Kolijn, Beáta Bódi, Roua Hassoun, Melina Tangos, Saltanat Zhazykbayeva, Ágnes Balogh, Dániel Czuriga, Sophie Van Linthout, Carsten Tschöpe, Naranjan S. Dhalla, Andreas Mügge, Attila Tóth, Zoltán Papp, Judit Barta, Nazha Hamdani
Published 2021-06-01

Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator

by Detmar Kolijn, Detmar Kolijn, Detmar Kolijn, Detmar Kolijn, Árpád Kovács, Árpád Kovács, Árpád Kovács, Árpád Kovács, Melissa Herwig, Melissa Herwig, Melissa Herwig, Melissa Herwig, Mária Lódi, Mária Lódi, Mária Lódi, Mária Lódi, Mária Lódi, Marcel Sieme, Marcel Sieme, Abdulatif Alhaj, Abdulatif Alhaj, Abdulatif Alhaj, Peter Sandner, Zoltán Papp, Peter H. Reusch, Peter Haldenwang, Ines Falcão-Pires, Wolfgang A. Linke, Kornelia Jaquet, Kornelia Jaquet, Kornelia Jaquet, Sophie Van Linthout, Andreas Mügge, Andreas Mügge, Carsten Tschöpe, Nazha Hamdani, Nazha Hamdani, Nazha Hamdani, Nazha Hamdani
Published 2020-05-01