Decoding the Structural Bases of D76N ß2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.

by Matteo de Rosa, Alberto Barbiroli, Sofia Giorgetti, Patrizia P Mangione, Martino Bolognesi, Stefano Ricagno
Published 2015-01-01

Wild type beta-2 microglobulin and DE loop mutants display a common fibrillar architecture.

by Antonino Natalello, Annalisa Relini, Amanda Penco, Levon Halabelian, Martino Bolognesi, Silvia Maria Doglia, Stefano Ricagno
Published 2015-01-01

Investigating the Molecular Basis of the Aggregation Propensity of the Pathological D76N Mutant of Beta-2 Microglobulin: Role of the Denatured State

by Lorenzo Visconti, Francesca Malagrinò, Luca Broggini, Chiara Maria Giulia De Luca, Fabio Moda, Stefano Gianni, Stefano Ricagno, Angelo Toto
Published 2019-01-01

The tempered polymerization of human neuroserpin.

by Rosina Noto, Maria Grazia Santangelo, Stefano Ricagno, Maria Rosalia Mangione, Matteo Levantino, Margherita Pezzullo, Vincenzo Martorana, Antonio Cupane, Martino Bolognesi, Mauro Manno
Published 2012-01-01

Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors

by Cristina Visentin, Loana Musso, Luca Broggini, Francesca Bonato, Rosaria Russo, Claudia Moriconi, Martino Bolognesi, Elena Miranda, Sabrina Dallavalle, Daniele Passarella, Stefano Ricagno
Published 2020-07-01

Functionally Divergent Splicing Variants of the Rice AGAMOUS Ortholog OsMADS3 Are Evolutionary Conserved in Grasses

by Ludovico Dreni, Andrea Ravasio, Nahuel Gonzalez-Schain, Sara Jacchia, Glacy Jaqueline da Silva, Stefano Ricagno, Rosaria Russo, Francesca Caselli, Veronica Gregis, Martin M. Kater
Published 2020-05-01

Glycosylation Tunes Neuroserpin Physiological and Pathological Properties

by Cristina Visentin, Luca Broggini, Benedetta Maria Sala, Rosaria Russo, Alberto Barbiroli, Carlo Santambrogio, Simona Nonnis, Anatoly Dubnovitsky, Martino Bolognesi, Elena Miranda, Adnane Achour, Stefano Ricagno
Published 2020-05-01

Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient

by Paolo Swuec, Francesca Lavatelli, Masayoshi Tasaki, Cristina Paissoni, Paola Rognoni, Martina Maritan, Francesca Brambilla, Paolo Milani, Pierluigi Mauri, Carlo Camilloni, Giovanni Palladini, Giampaolo Merlini, Stefano Ricagno, Martino Bolognesi
Published 2019-03-01

Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity

by Tanguy Le Marchand, Matteo de Rosa, Nicola Salvi, Benedetta Maria Sala, Loren B. Andreas, Emeline Barbet-Massin, Pietro Sormanni, Alberto Barbiroli, Riccardo Porcari, Cristiano Sousa Mota, Daniele de Sanctis, Martino Bolognesi, Lyndon Emsley, Vittorio Bellotti, Martin Blackledge, Carlo Camilloni, Guido Pintacuda, Stefano Ricagno
Published 2018-04-01