Dual neutralisation of IL-17F and IL-17A with bimekizumab blocks inflammation-driven osteogenic differentiation of human periosteal cells

by Dominique Baeten, Stevan Shaw, Mittal Shah, Asher Maroof, Panos Gikas, Gayatri Mittal, Richard Keen, Scott J Roberts
Published 2020-08-01

Interleukin (IL)-12 and IL-18 Synergize to Promote MAIT Cell IL-17A and IL-17F Production Independently of IL-23 Signaling

by Suzanne Cole, Janine Murray, Catherine Simpson, Remi Okoye, Kerry Tyson, Meryn Griffiths, Dominique Baeten, Stevan Shaw, Asher Maroof
Published 2020-11-01

Bimekizumab, a Novel Humanized IgG1 Antibody That Neutralizes Both IL-17A and IL-17F

by Ralph Adams, Asher Maroof, Terry Baker, Alastair D. G. Lawson, Ruth Oliver, Ross Paveley, Steve Rapecki, Stevan Shaw, Pavan Vajjah, Shauna West, Meryn Griffiths
Published 2020-08-01

Interleukin-6 contributes to inflammation and remodeling in a model of adenosine mediated lung injury.

by Mesias Pedroza, Daniel J Schneider, Harry Karmouty-Quintana, Julie Coote, Stevan Shaw, Rebecca Corrigan, Jose G Molina, Joseph L Alcorn, David Galas, Richard Gelinas, Michael R Blackburn
Published 2011-01-01