Detection of singularity in immunity and cancer by novel imaging techniques

by Takeharu Nagai, Shunsuke Chikuma, Kenjiro Hanaoka
Published 2020-09-01

Fluorescent Proteins for Investigating Biological Events in Acidic Environments

by Hajime Shinoda, Michael Shannon, Takeharu Nagai
Published 2018-05-01

Fluorescent Protein-Based Indicators for Functional Super-Resolution Imaging of Biomolecular Activities in Living Cells

by Kai Lu, Cong Quang Vu, Tomoki Matsuda, Takeharu Nagai
Published 2019-11-01

Green monomeric photosensitizing fluorescent protein for photo-inducible protein inactivation and cell ablation

by Yemima Dani Riani, Tomoki Matsuda, Kiwamu Takemoto, Takeharu Nagai
Published 2018-04-01

A highly-sensitive genetically encoded temperature indicator exploiting a temperature-responsive elastin-like polypeptide

by Cong Quang Vu, Shun-ichi Fukushima, Tetsuichi Wazawa, Takeharu Nagai
Published 2021-08-01

Smartphone-Based Portable Bioluminescence Imaging System Enabling Observation at Various Scales from Whole Mouse Body to Organelle

by Mitsuru Hattori, Sumito Shirane, Tomoki Matsuda, Kuniaki Nagayama, Takeharu Nagai
Published 2020-12-01

Spectral fingerprinting of individual cells visualized by cavity-reflection-enhanced light-absorption microscopy.

by Yoshiyuki Arai, Takayuki Yamamoto, Takeo Minamikawa, Tetsuro Takamatsu, Takeharu Nagai
Published 2015-01-01

Enhanced brightness of bacterial luciferase by bioluminescence resonance energy transfer

by Tomomi Kaku, Kazunori Sugiura, Tetsuyuki Entani, Kenji Osabe, Takeharu Nagai
Published 2021-07-01

Bioluminescent Ratiometric Indicator for Analysis of Water Hardness in Household Water

by Md Nadim Hossain, Ryuichi Ishida, Mitsuru Hattori, Tomoki Matsuda, Takeharu Nagai
Published 2020-06-01

Genetically encoded ratiometric fluorescent thermometer with wide range and rapid response.

by Masahiro Nakano, Yoshiyuki Arai, Ippei Kotera, Kohki Okabe, Yasuhiro Kamei, Takeharu Nagai
Published 2017-01-01

An improved inverse-type Ca2+ indicator can detect putative neuronal inhibition in Caenorhabditis elegans by increasing signal intensity upon Ca2+ decrease.

by Sayuri Hara-Kuge, Tomonobu Nishihara, Tomoki Matsuda, Tomohiro Kitazono, Takayuki Teramoto, Takeharu Nagai, Takeshi Ishihara
Published 2018-01-01

Auto-luminescent genetically-encoded ratiometric indicator for real-time Ca2+ imaging at the single cell level.

by Kenta Saito, Noriyuki Hatsugai, Kazuki Horikawa, Kentaro Kobayashi, Toru Matsu-Ura, Katsuhiko Mikoshiba, Takeharu Nagai
Published 2010-01-01

Five colour variants of bright luminescent protein for real-time multicolour bioimaging

by Kazushi Suzuki, Taichi Kimura, Hajime Shinoda, Guirong Bai, Matthew J. Daniels, Yoshiyuki Arai, Masahiro Nakano, Takeharu Nagai
Published 2016-12-01

Uninterrupted monitoring of drug effects in human-induced pluripotent stem cell-derived cardiomyocytes with bioluminescence Ca2+ microscopy

by Kazushi Suzuki, Takahito Onishi, Chieko Nakada, Shunsuke Takei, Matthew J. Daniels, Masahiro Nakano, Tomoki Matsuda, Takeharu Nagai
Published 2018-05-01

Ultrasensitive Imaging of Ca2+ Dynamics in Pancreatic Acinar Cells of Yellow Cameleon-Nano Transgenic Mice

by Yusuke Oshima, Takeshi Imamura, Atsuko Shintani, Hiroko Kajiura-Kobayashi, Terumasa Hibi, Takeharu Nagai, Shigenori Nonaka, Tomomi Nemoto
Published 2014-11-01

Identification of mitochondrial DNA polymorphisms that alter mitochondrial matrix pH and intracellular calcium dynamics.

by An-a Kazuno, Kae Munakata, Takeharu Nagai, Satoshi Shimozono, Masashi Tanaka, Makoto Yoneda, Nobumasa Kato, Atsushi Miyawaki, Tadafumi Kato
Published 2006-08-01

Nonlinear Structured Illumination Using a Fluorescent Protein Activating at the Readout Wavelength.

by Hui-Wen Lu-Walther, Wenya Hou, Martin Kielhorn, Yoshiyuki Arai, Takeharu Nagai, Michael M Kessels, Britta Qualmann, Rainer Heintzmann
Published 2016-01-01

Intracellular calcium spikes in rat suprachiasmatic nucleus neurons induced by BAPTA-based calcium dyes.

by Jin Hee Hong, Cheol Hong Min, Byeongha Jeong, Tomoyoshi Kojiya, Eri Morioka, Takeharu Nagai, Masayuki Ikeda, Kyoung J Lee
Published 2010-01-01

Optical recording of neuronal activity with a genetically-encoded calcium indicator in anesthetized and freely moving mice

by Henry Lütcke, Masanori Murayama, Masanori Murayama, Thomas Hahn, Thomas Hahn, David J Margolis, Simone Astori, Simone Astori, Stephan Meyer, Werner Göbel, Ying Yang, Wannan Tang, Sebastian Kügler, Rolf Sprengel, Takeharu Nagai, Takeharu Nagai, Atsushi Miyawaki, Matthew E Larkum, Fritjof Helmchen, Mazahir T Hasan
Published 2010-04-01

Non-invasive phenotyping and drug testing in single cardiomyocytes or beta-cells by calcium imaging and optogenetics.

by Yu-Fen Chang, Connor N Broyles, Frances A Brook, Mark J Davies, Cameron W Turtle, Takeharu Nagai, Matthew J Daniels
Published 2017-01-01