A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of Ik1 Ion Channels in Real-Tim...

by Birgit Goversen, Nadine Becker, Sonja Stoelzle-Feix, Alison Obergrussberger, Marc A. Vos, Toon A. B. van Veen, Niels Fertig, Teun P. de Boer
Published 2018-01-01

Experimental mapping of the canine KCNJ2 and KCNJ12 gene structures and functional analysis of the canine KIR2.2 ion channel

by Marien J.C. Houtman, Hiroki eTakanari, Bart G.J.M. Kok, Margot evan Eck, Denise R. Montagne, Marc A. Vos, Teun P de Boer, Marcel A.G. van der Heyden
Published 2012-01-01

Changes in Cx43 and NaV1.5 expression precede the occurrence of substantial fibrosis in calcineurin-induced murine cardiac hypertrophy.

by Magda S C Fontes, Antonia J A Raaijmakers, Tessa van Doorn, Bart Kok, Sylvia Nieuwenhuis, Roel van der Nagel, Marc A Vos, Teun P de Boer, Harold V M van Rijen, Marti F A Bierhuizen
Published 2014-01-01

Genetic variation in GNB5 causes bradycardia by augmenting the cholinergic response via increased acetylcholine-activated potassium current (IK,ACh)

by Christiaan C. Veerman, Isabella Mengarelli, Charlotte D. Koopman, Ronald Wilders, Shirley C. van Amersfoorth, Diane Bakker, Rianne Wolswinkel, Mariam Hababa, Teun P. de Boer, Kaomei Guan, James Milnes, Elisabeth M. Lodder, Jeroen Bakkers, Arie O. Verkerk, Connie R. Bezzina
Published 2019-07-01