A Biologically-Based Computational Approach to Drug Repurposing for Anthrax Infection

by Jane P. F. Bai, Theodore Sakellaropoulos, Leonidas G. Alexopoulos
Published 2017-03-01

Network reconstruction based on proteomic data and prior knowledge of protein connectivity using graph theory.

by Vassilis Stavrakas, Ioannis N Melas, Theodore Sakellaropoulos, Leonidas G Alexopoulos
Published 2015-01-01

Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries

by Yixiao Gong, Charalampos Lazaris, Theodore Sakellaropoulos, Aurelie Lozano, Prabhanjan Kambadur, Panagiotis Ntziachristos, Iannis Aifantis, Aristotelis Tsirigos
Published 2018-02-01

NSD2 overexpression drives clustered chromatin and transcriptional changes in a subset of insulated domains

by Priscillia Lhoumaud, Sana Badri, Javier Rodriguez-Hernaez, Theodore Sakellaropoulos, Gunjan Sethia, Andreas Kloetgen, MacIntosh Cornwell, Sourya Bhattacharyya, Ferhat Ay, Richard Bonneau, Aristotelis Tsirigos, Jane A. Skok
Published 2019-10-01

EpiMethylTag: simultaneous detection of ATAC-seq or ChIP-seq signals with DNA methylation

by Priscillia Lhoumaud, Gunjan Sethia, Franco Izzo, Theodore Sakellaropoulos, Valentina Snetkova, Simon Vidal, Sana Badri, Macintosh Cornwell, Dafne Campigli Di Giammartino, Kyu-Tae Kim, Effie Apostolou, Matthias Stadtfeld, Dan Avi Landau, Jane Skok
Published 2019-11-01

Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis

by Marti Bernardo-Faura, Melanie Rinas, Jakob Wirbel, Inna Pertsovskaya, Vicky Pliaka, Dimitris E. Messinis, Gemma Vila, Theodore Sakellaropoulos, Wolfgang Faigle, Pernilla Stridh, Janina R. Behrens, Tomas Olsson, Roland Martin, Friedemann Paul, Leonidas G. Alexopoulos, Pablo Villoslada, Julio Saez-Rodriguez
Published 2021-07-01

Selective cytotoxicity of the herbal substance acteoside against tumor cells and its mechanistic insights

by Christina Cheimonidi, Pinelopi Samara, Panagiotis Polychronopoulos, Eleni N. Tsakiri, Theodora Nikou, Vassilios Myrianthopoulos, Theodore Sakellaropoulos, Vassilis Zoumpourlis, Emmanuel Mikros, Issidora Papassideri, Aikaterini Argyropoulou, Maria Halabalaki, Leonidas G. Alexopoulos, Alexios-Leandros Skaltsounis, Ourania E. Tsitsilonis, Nektarios N. Aligiannis, Ioannis P. Trougakos
Published 2018-06-01

A Deep Learning Framework for Predicting Response to Therapy in Cancer

by Theodore Sakellaropoulos, Konstantinos Vougas, Sonali Narang, Filippos Koinis, Athanassios Kotsinas, Alexander Polyzos, Tyler J. Moss, Sarina Piha-Paul, Hua Zhou, Eleni Kardala, Eleni Damianidou, Leonidas G. Alexopoulos, Iannis Aifantis, Paul A. Townsend, Mihalis I. Panayiotidis, Petros Sfikakis, Jiri Bartek, Rebecca C. Fitzgerald, Dimitris Thanos, Kenna R. Mills Shaw, Russell Petty, Aristotelis Tsirigos, Vassilis G. Gorgoulis
Published 2019-12-01