lncRNA-screen: an interactive platform for computationally screening long non-coding RNAs in large genomics datasets

by Yixiao Gong, Hsuan-Ting Huang, Yu Liang, Thomas Trimarchi, Iannis Aifantis, Aristotelis Tsirigos
Published 2017-06-01

Analysis of TET2 mutations in paroxysmal nocturnal hemoglobinuria (PNH)

by Camille Lobry, Ashish Bains, Leah B. Zamechek, Sherif Ibrahim, Iannis Aifantis, David J. Araten
Published 2019-08-01

Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries

by Yixiao Gong, Charalampos Lazaris, Theodore Sakellaropoulos, Aurelie Lozano, Prabhanjan Kambadur, Panagiotis Ntziachristos, Iannis Aifantis, Aristotelis Tsirigos
Published 2018-02-01

The CUL4-DDB1 ubiquitin ligase complex controls adult and embryonic stem cell differentiation and homeostasis

by Jie Gao, Shannon M Buckley, Luisa Cimmino, Maria Guillamot, Alexandros Strikoudis, Yong Cang, Stephen P Goff, Iannis Aifantis
Published 2015-11-01

STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia

by Shella Saint Fleur-Lominy, Mate Maus, Martin Vaeth, Ingo Lange, Isabelle Zee, David Suh, Cynthia Liu, Xiaojun Wu, Anastasia Tikhonova, Iannis Aifantis, Stefan Feske
Published 2018-09-01

Active and Inactive Enhancers Cooperate to Exert Localized and Long-Range Control of Gene Regulation

by Charlotte Proudhon, Valentina Snetkova, Ramya Raviram, Camille Lobry, Sana Badri, Tingting Jiang, Bingtao Hao, Thomas Trimarchi, Yuval Kluger, Iannis Aifantis, Richard Bonneau, Jane A. Skok
Published 2016-06-01

Endothelial Jagged-1 Is Necessary for Homeostatic and Regenerative Hematopoiesis

by Michael G. Poulos, Peipei Guo, Natalie M. Kofler, Sandra Pinho, Michael C. Gutkin, Anastasia Tikhonova, Iannis Aifantis, Paul S. Frenette, Jan Kitajewski, Shahin Rafii, Jason M. Butler
Published 2013-09-01

AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis

by Matt Teater, Pilar M. Dominguez, David Redmond, Zhengming Chen, Daisuke Ennishi, David W. Scott, Luisa Cimmino, Paola Ghione, Jayanta Chaudhuri, Randy D. Gascoyne, Iannis Aifantis, Giorgio Inghirami, Olivier Elemento, Ari Melnick, Rita Shaknovich
Published 2018-01-01

Higher-Order Looping and Nuclear Organization of Tcra Facilitate Targeted RAG Cleavage and Regulated Rearrangement in Recombination Centers

by Julie Chaumeil, Mariann Micsinai, Panagiotis Ntziachristos, Ludovic Deriano, Joy M.-H. Wang, Yanhong Ji, Elphege P. Nora, Matthew J. Rodesch, Jeffrey A. Jeddeloh, Iannis Aifantis, Yuval Kluger, David G. Schatz, Jane A. Skok
Published 2013-02-01

Control of Embryonic Stem Cell Identity by BRD4-Dependent Transcriptional Elongation of Super-Enhancer-Associated Pluripotency Genes

by Raffaella Di Micco, Barbara Fontanals-Cirera, Vivien Low, Panagiotis Ntziachristos, Stephanie K. Yuen, Claudia D. Lovell, Igor Dolgalev, Yoshiya Yonekubo, Guangtao Zhang, Elena Rusinova, Guillermo Gerona-Navarro, Marta Cañamero, Michael Ohlmeyer, Iannis Aifantis, Ming-Ming Zhou, Aristotelis Tsirigos, Eva Hernando
Published 2014-10-01

A Deep Learning Framework for Predicting Response to Therapy in Cancer

by Theodore Sakellaropoulos, Konstantinos Vougas, Sonali Narang, Filippos Koinis, Athanassios Kotsinas, Alexander Polyzos, Tyler J. Moss, Sarina Piha-Paul, Hua Zhou, Eleni Kardala, Eleni Damianidou, Leonidas G. Alexopoulos, Iannis Aifantis, Paul A. Townsend, Mihalis I. Panayiotidis, Petros Sfikakis, Jiri Bartek, Rebecca C. Fitzgerald, Dimitris Thanos, Kenna R. Mills Shaw, Russell Petty, Aristotelis Tsirigos, Vassilis G. Gorgoulis
Published 2019-12-01

Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells

by Feng Pan, Thomas S. Wingo, Zhigang Zhao, Rui Gao, Hideki Makishima, Guangbo Qu, Li Lin, Miao Yu, Janice R. Ortega, Jiapeng Wang, Aziz Nazha, Li Chen, Bing Yao, Can Liu, Shi Chen, Ophelia Weeks, Hongyu Ni, Brittany Lynn Phillips, Suming Huang, Jianlong Wang, Chuan He, Guo-Min Li, Tomas Radivoyevitch, Iannis Aifantis, Jaroslaw P. Maciejewski, Feng-Chun Yang, Peng Jin, Mingjiang Xu
Published 2017-04-01

Author Correction: The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

by Dimitrios Papaioannou, Andreas Petri, Oliver M. Dovey, Sara Terreri, Eric Wang, Frances A. Collins, Lauren A. Woodward, Allison E. Walker, Deedra Nicolet, Felice Pepe, Prasanthi Kumchala, Marius Bill, Christopher J. Walker, Malith Karunasiri, Krzysztof Mrózek, Miranda L. Gardner, Virginia Camilotto, Nina Zitzer, Jonathan L. Cooper, Xiongwei Cai, Xiaoqing Rong-Mullins, Jessica Kohlschmidt, Kellie J. Archer, Michael A. Freitas, Yi Zheng, Robert J. Lee, Iannis Aifantis, George Vassiliou, Guramrit Singh, Sakari Kauppinen, Clara D. Bloomfield, Adrienne M. Dorrance, Ramiro Garzon
Published 2020-07-01

The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

by Dimitrios Papaioannou, Andreas Petri, Oliver M. Dovey, Sara Terreri, Eric Wang, Frances A. Collins, Lauren A. Woodward, Allison E. Walker, Deedra Nicolet, Felice Pepe, Prasanthi Kumchala, Marius Bill, Christopher J. Walker, Malith Karunasiri, Krzysztof Mrózek, Miranda L. Gardner, Virginia Camilotto, Nina Zitzer, Jonathan L. Cooper, Xiongwei Cai, Xiaoqing Rong-Mullins, Jessica Kohlschmidt, Kellie J. Archer, Michael A. Freitas, Yi Zheng, Robert J. Lee, Iannis Aifantis, George Vassiliou, Guramrit Singh, Sakari Kauppinen, Clara D. Bloomfield, Adrienne M. Dorrance, Ramiro Garzon
Published 2019-11-01

Publisher Correction: The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

by Dimitrios Papaioannou, Andreas Petri, Oliver M. Dovey, Sara Terreri, Eric Wang, Frances A. Collins, Lauren A. Woodward, Allison E. Walker, Deedra Nicolet, Felice Pepe, Prasanthi Kumchala, Marius Bill, Christopher J. Walker, Malith Karunasiri, Krzysztof Mrózek, Miranda L. Gardner, Virginia Camilotto, Nina Zitzer, Jonathan L. Cooper, Xiongwei Cai, Xiaoqing Rong-Mullins, Jessica Kohlschmidt, Kellie J. Archer, Michael A. Freitas, Yi Zheng, Robert J. Lee, Iannis Aifantis, George Vassiliou, Guramrit Singh, Sakari Kauppinen, Clara D. Bloomfield, Adrienne M. Dorrance, Ramiro Garzon
Published 2020-01-01

DNA Hydroxymethylation Profiling Reveals that WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia

by Raajit Rampal, Altuna Alkalin, Jozef Madzo, Aparna Vasanthakumar, Elodie Pronier, Jay Patel, Yushan Li, Jihae Ahn, Omar Abdel-Wahab, Alan Shih, Chao Lu, Patrick S. Ward, Jennifer J. Tsai, Todd Hricik, Valeria Tosello, Jacob E. Tallman, Xinyang Zhao, Danette Daniels, Qing Dai, Luisa Ciminio, Iannis Aifantis, Chuan He, Francois Fuks, Martin S. Tallman, Adolfo Ferrando, Stephen Nimer, Elisabeth Paietta, Craig B. Thompson, Jonathan D. Licht, Christopher E. Mason, Lucy A. Godley, Ari Melnick, Maria E. Figueroa, Ross L. Levine
Published 2014-12-01