Myeloid Malignancies with Chromosome 5q Deletions Acquire a Dependency on an Intrachromosomal NF-κB Gene Network

by Jing Fang, Brenden Barker, Lyndsey Bolanos, Xiaona Liu, Andres Jerez, Hideki Makishima, Susanne Christie, Xiaoting Chen, Dinesh S. Rao, H. Leighton Grimes, Kakajan Komurov, Matthew T. Weirauch, Jose A. Cancelas, Jaroslaw P. Maciejewski, Daniel T. Starczynowski
Published 2014-09-01

Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia

by Yusuke Shiozawa, Luca Malcovati, Anna Gallì, Aiko Sato-Otsubo, Keisuke Kataoka, Yusuke Sato, Yosaku Watatani, Hiromichi Suzuki, Tetsuichi Yoshizato, Kenichi Yoshida, Masashi Sanada, Hideki Makishima, Yuichi Shiraishi, Kenichi Chiba, Eva Hellström-Lindberg, Satoru Miyano, Seishi Ogawa, Mario Cazzola
Published 2018-09-01

Aberrant DNA Methylation Is Associated with a Poor Outcome in Juvenile Myelomonocytic Leukemia.

by Hirotoshi Sakaguchi, Hideki Muramatsu, Yusuke Okuno, Hideki Makishima, Yinyan Xu, Yoko Furukawa-Hibi, Xinan Wang, Atsushi Narita, Kenichi Yoshida, Yuichi Shiraishi, Sayoko Doisaki, Nao Yoshida, Asahito Hama, Yoshiyuki Takahashi, Kiyofumi Yamada, Satoru Miyano, Seishi Ogawa, Jaroslaw P Maciejewski, Seiji Kojima
Published 2015-01-01

Single nucleotide polymorphism array lesions, TET2, DNMT3A, ASXL1 and CBL mutations are present in systemic mastocytosis.

by Fabiola Traina, Valeria Visconte, Anna M Jankowska, Hideki Makishima, Christine L O'Keefe, Paul Elson, Yingchun Han, Fred H Hsieh, Mikkael A Sekeres, Raghuveer Singh Mali, Matt Kalaycio, Alan E Lichtin, Anjali S Advani, Hien K Duong, Edward Copelan, Reuben Kapur, Sara T Olalla Saad, Jaroslaw P Maciejewski, Ramon V Tiu
Published 2012-01-01

Invariant patterns of clonal succession determine specific clinical features of myelodysplastic syndromes

by Yasunobu Nagata, Hideki Makishima, Cassandra M. Kerr, Bartlomiej P. Przychodzen, Mai Aly, Abhinav Goyal, Hassan Awada, Mohammad Fahad Asad, Teodora Kuzmanovic, Hiromichi Suzuki, Tetsuichi Yoshizato, Kenichi Yoshida, Kenichi Chiba, Hiroko Tanaka, Yuichi Shiraishi, Satoru Miyano, Sudipto Mukherjee, Thomas LaFramboise, Aziz Nazha, Mikkael A. Sekeres, Tomas Radivoyevitch, Torsten Haferlach, Seishi Ogawa, Jaroslaw P. Maciejewski
Published 2019-11-01

Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells

by Feng Pan, Thomas S. Wingo, Zhigang Zhao, Rui Gao, Hideki Makishima, Guangbo Qu, Li Lin, Miao Yu, Janice R. Ortega, Jiapeng Wang, Aziz Nazha, Li Chen, Bing Yao, Can Liu, Shi Chen, Ophelia Weeks, Hongyu Ni, Brittany Lynn Phillips, Suming Huang, Jianlong Wang, Chuan He, Guo-Min Li, Tomas Radivoyevitch, Iannis Aifantis, Jaroslaw P. Maciejewski, Feng-Chun Yang, Peng Jin, Mingjiang Xu
Published 2017-04-01

Clonal evolution and clinical implications of genetic abnormalities in blastic transformation of chronic myeloid leukaemia

by Yotaro Ochi, Kenichi Yoshida, Ying-Jung Huang, Ming-Chung Kuo, Yasuhito Nannya, Ko Sasaki, Kinuko Mitani, Noriko Hosoya, Nobuhiro Hiramoto, Takayuki Ishikawa, Susan Branford, Naranie Shanmuganathan, Kazuma Ohyashiki, Naoto Takahashi, Tomoiku Takaku, Shun Tsuchiya, Nobuhiro Kanemura, Nobuhiko Nakamura, Yasunori Ueda, Satoshi Yoshihara, Rabindranath Bera, Yusuke Shiozawa, Lanying Zhao, June Takeda, Yosaku Watatani, Rurika Okuda, Hideki Makishima, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Masashi Sanada, Akifumi Takaori-Kondo, Satoru Miyano, Seishi Ogawa, Lee-Yung Shih
Published 2021-05-01