Overexpressed HSF1 cancer signature genes cluster in human chromosome 8q

by Christopher Q. Zhang, Heinric Williams, Thomas L. Prince, Eric S. Ho
Published 2017-12-01

MZF1 and SCAND1 Reciprocally Regulate <i>CDC37</i> Gene Expression in Prostate Cancer

by Takanori Eguchi, Thomas L. Prince, Manh Tien Tran, Chiharu Sogawa, Benjamin J. Lang, Stuart K. Calderwood
Published 2019-06-01

Heat Shock Proteins Are Essential Components in Transformation and Tumor Progression: Cancer Cell Intrinsic Pathways and Beyond

by Benjamin J. Lang, Martín Eduardo Guerrero-Giménez, Thomas L. Prince, Andrew Ackerman, Cristina Bonorino, Stuart K. Calderwood
Published 2019-09-01

HSF1: Primary Factor in Molecular Chaperone Expression and a Major Contributor to Cancer Morbidity

by Thomas L. Prince, Benjamin J. Lang, Martin E. Guerrero-Gimenez, Juan Manuel Fernandez-Muñoz, Andrew Ackerman, Stuart K. Calderwood
Published 2020-04-01

Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants.

by Thomas L Prince, Toshiki Kijima, Manabu Tatokoro, Sunmin Lee, Shinji Tsutsumi, Kendrick Yim, Candy Rivas, Sylvia Alarcon, Harvey Schwartz, Kofi Khamit-Kush, Bradley T Scroggins, Kristin Beebe, Jane B Trepel, Len Neckers
Published 2015-01-01

HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation

by Toshiki Kijima, Thomas L. Prince, Megan L. Tigue, Kendrick H. Yim, Harvey Schwartz, Kristin Beebe, Sunmin Lee, Marek A. Budzynski, Heinric Williams, Jane B. Trepel, Lea Sistonen, Stuart Calderwood, Len Neckers
Published 2018-05-01