Expression and function of PML-RARA in the hematopoietic progenitor cells of Ctsg-PML-RARA mice.

by Lukas D Wartman, John S Welch, Geoffrey L Uy, Jeffery M Klco, Tamara Lamprecht, Nobish Varghese, Rakesh Nagarajan, Timothy J Ley
Published 2012-01-01

A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing

by Allegra A. Petti, Stephen R. Williams, Christopher A. Miller, Ian T. Fiddes, Sridhar N. Srivatsan, David Y. Chen, Catrina C. Fronick, Robert S. Fulton, Deanna M. Church, Timothy J. Ley
Published 2019-08-01

A high-resolution map of segmental DNA copy number variation in the mouse genome.

by Timothy A Graubert, Patrick Cahan, Deepa Edwin, Rebecca R Selzer, Todd A Richmond, Peggy S Eis, William D Shannon, Xia Li, Howard L McLeod, James M Cheverud, Timothy J Ley
Published 2007-01-01

Genetic heterogeneity of induced pluripotent stem cells: results from 24 clones derived from a single C57BL/6 mouse.

by Cheng Li, Jeffery M Klco, Nichole M Helton, Daniel R George, Jacqueline L Mudd, Christopher A Miller, Charles Lu, Robert Fulton, Michelle O'Laughlin, Catrina Fronick, Richard K Wilson, Timothy J Ley
Published 2015-01-01

SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution.

by Christopher A Miller, Brian S White, Nathan D Dees, Malachi Griffith, John S Welch, Obi L Griffith, Ravi Vij, Michael H Tomasson, Timothy A Graubert, Matthew J Walter, Matthew J Ellis, William Schierding, John F DiPersio, Timothy J Ley, Elaine R Mardis, Richard K Wilson, Li Ding
Published 2014-08-01

Functional and epigenetic phenotypes of humans and mice with DNMT3A Overgrowth Syndrome

by Amanda M. Smith, Taylor A. LaValle, Marwan Shinawi, Sai M. Ramakrishnan, Haley J. Abel, Cheryl A. Hill, Nicole M. Kirkland, Michael P. Rettig, Nichole M. Helton, Sharon E. Heath, Francesca Ferraro, David Y. Chen, Sangeeta Adak, Clay F. Semenkovich, Diana L. Christian, Jenna R. Martin, Harrison W. Gabel, Christopher A. Miller, Timothy J. Ley
Published 2021-07-01

Clonal architectures and driver mutations in metastatic melanomas.

by Li Ding, Minjung Kim, Krishna L Kanchi, Nathan D Dees, Charles Lu, Malachi Griffith, David Fenstermacher, Hyeran Sung, Christopher A Miller, Brian Goetz, Michael C Wendl, Obi Griffith, Lynn A Cornelius, Gerald P Linette, Joshua F McMichael, Vernon K Sondak, Ryan C Fields, Timothy J Ley, James J Mulé, Richard K Wilson, Jeffrey S Weber
Published 2014-01-01

Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression

by Jessica M. Silva-Fisher, Ha X. Dang, Nicole M. White, Matthew S. Strand, Bradley A. Krasnick, Emily B. Rozycki, Gejae G. L. Jeffers, Julie G. Grossman, Maureen K. Highkin, Cynthia Tang, Christopher R. Cabanski, Abdallah Eteleeb, Jacqueline Mudd, S. Peter Goedegebuure, Jingqin Luo, Elaine R. Mardis, Richard K. Wilson, Timothy J. Ley, Albert C. Lockhart, Ryan C. Fields, Christopher A. Maher
Published 2020-05-01

Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing.

by Andrew E O Hughes, Vincent Magrini, Ryan Demeter, Christopher A Miller, Robert Fulton, Lucinda L Fulton, William C Eades, Kevin Elliott, Sharon Heath, Peter Westervelt, Li Ding, Donald F Conrad, Brian S White, Jin Shao, Daniel C Link, John F DiPersio, Elaine R Mardis, Richard K Wilson, Timothy J Ley, Matthew J Walter, Timothy A Graubert
Published 2014-07-01

Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential

by Terrence N. Wong, Christopher A. Miller, Matthew R. M. Jotte, Nusayba Bagegni, Jack D. Baty, Amy P. Schmidt, Amanda F. Cashen, Eric J. Duncavage, Nichole M. Helton, Mark Fiala, Robert S. Fulton, Sharon E. Heath, Megan Janke, Kierstin Luber, Peter Westervelt, Ravi Vij, John F. DiPersio, John S. Welch, Timothy A. Graubert, Matthew J. Walter, Timothy J. Ley, Daniel C. Link
Published 2018-01-01

Co-evolution of tumor and immune cells during progression of multiple myeloma

by Ruiyang Liu, Qingsong Gao, Steven M. Foltz, Jared S. Fowles, Lijun Yao, Julia Tianjiao Wang, Song Cao, Hua Sun, Michael C. Wendl, Sunantha Sethuraman, Amila Weerasinghe, Michael P. Rettig, Erik P. Storrs, Christopher J. Yoon, Matthew A. Wyczalkowski, Joshua F. McMichael, Daniel R. Kohnen, Justin King, Scott R. Goldsmith, Julie O’Neal, Robert S. Fulton, Catrina C. Fronick, Timothy J. Ley, Reyka G. Jayasinghe, Mark A. Fiala, Stephen T. Oh, John F. DiPersio, Ravi Vij, Li Ding
Published 2021-05-01