Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis.

by Timothy A Graubert, Michelle A Payton, Jin Shao, Richard A Walgren, Ryan S Monahan, John L Frater, Mark A Walshauser, Mike G Martin, Yumi Kasai, Matthew J Walter
Published 2009-01-01

A high-resolution map of segmental DNA copy number variation in the mouse genome.

by Timothy A Graubert, Patrick Cahan, Deepa Edwin, Rebecca R Selzer, Todd A Richmond, Peggy S Eis, William D Shannon, Xia Li, Howard L McLeod, James M Cheverud, Timothy J Ley
Published 2007-01-01

Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome

by Cara Lunn Shirai, Brian S. White, Manorama Tripathi, Roberto Tapia, James N. Ley, Matthew Ndonwi, Sanghyun Kim, Jin Shao, Alexa Carver, Borja Saez, Robert S. Fulton, Catrina Fronick, Michelle O’Laughlin, Chandraiah Lagisetti, Thomas R. Webb, Timothy A. Graubert, Matthew J. Walter
Published 2017-01-01

SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution.

by Christopher A Miller, Brian S White, Nathan D Dees, Malachi Griffith, John S Welch, Obi L Griffith, Ravi Vij, Michael H Tomasson, Timothy A Graubert, Matthew J Walter, Matthew J Ellis, William Schierding, John F DiPersio, Timothy J Ley, Elaine R Mardis, Richard K Wilson, Li Ding
Published 2014-08-01

Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing.

by Andrew E O Hughes, Vincent Magrini, Ryan Demeter, Christopher A Miller, Robert Fulton, Lucinda L Fulton, William C Eades, Kevin Elliott, Sharon Heath, Peter Westervelt, Li Ding, Donald F Conrad, Brian S White, Jin Shao, Daniel C Link, John F DiPersio, Elaine R Mardis, Richard K Wilson, Timothy J Ley, Matthew J Walter, Timothy A Graubert
Published 2014-07-01

Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential

by Terrence N. Wong, Christopher A. Miller, Matthew R. M. Jotte, Nusayba Bagegni, Jack D. Baty, Amy P. Schmidt, Amanda F. Cashen, Eric J. Duncavage, Nichole M. Helton, Mark Fiala, Robert S. Fulton, Sharon E. Heath, Megan Janke, Kierstin Luber, Peter Westervelt, Ravi Vij, John F. DiPersio, John S. Welch, Timothy A. Graubert, Matthew J. Walter, Timothy J. Ley, Daniel C. Link
Published 2018-01-01