ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest

by Aya Noguchi, Shungo Adachi, Naoto Yokota, Tomohisa Hatta, Tohru Natsume, Hiroyuki Kawahara
Published 2018-03-01

β-adrenergic receptor signaling evokes the PKA-ASK axis in mature brown adipocytes.

by Kazuki Hattori, Hiroaki Wakatsuki, Chihiro Sakauchi, Shotaro Furutani, Sho Sugawara, Tomohisa Hatta, Tohru Natsume, Hidenori Ichijo
Published 2020-01-01

Loss of Parkinson’s disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c

by Hongrui Meng, Chikara Yamashita, Kahori Shiba-Fukushima, Tsuyoshi Inoshita, Manabu Funayama, Shigeto Sato, Tomohisa Hatta, Tohru Natsume, Masataka Umitsu, Junichi Takagi, Yuzuru Imai, Nobutaka Hattori
Published 2017-06-01

Pre-emptive Quality Control Protects the ER from Protein Overload via the Proximity of ERAD Components and SRP

by Hisae Kadowaki, Atsushi Nagai, Takeshi Maruyama, Yasunari Takami, Pasjan Satrimafitrah, Hironori Kato, Arata Honda, Tomohisa Hatta, Tohru Natsume, Takashi Sato, Hirofumi Kai, Hidenori Ichijo, Hideki Nishitoh
Published 2015-11-01

Identification of a herpes simplex virus 1 gene encoding neurovirulence factor by chemical proteomics

by Akihisa Kato, Shungo Adachi, Shuichi Kawano, Kousuke Takeshima, Mizuki Watanabe, Shinobu Kitazume, Ryota Sato, Hideo Kusano, Naoto Koyanagi, Yuhei Maruzuru, Jun Arii, Tomohisa Hatta, Tohru Natsume, Yasushi Kawaguchi
Published 2020-09-01

TRIM48 Promotes ASK1 Activation and Cell Death through Ubiquitination-Dependent Degradation of the ASK1-Negative Regulator PRMT1

by Yusuke Hirata, Kazumi Katagiri, Keita Nagaoka, Tohru Morishita, Yuki Kudoh, Tomohisa Hatta, Isao Naguro, Kuniyuki Kano, Tsuyoshi Udagawa, Tohru Natsume, Junken Aoki, Toshifumi Inada, Takuya Noguchi, Hidenori Ichijo, Atsushi Matsuzawa
Published 2017-11-01

Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells

by Tatsuyuki Matsudaira, Kojiro Mukai, Taishin Noguchi, Junya Hasegawa, Tomohisa Hatta, Shun-ichiro Iemura, Tohru Natsume, Norio Miyamura, Hiroshi Nishina, Jun Nakayama, Kentaro Semba, Takuya Tomita, Shigeo Murata, Hiroyuki Arai, Tomohiko Taguchi
Published 2017-11-01