Baculovirus as a Tool for Gene Delivery and Gene Therapy

by Chikako Ono, Toru Okamoto, Takayuki Abe, Yoshiharu Matsuura
Published 2018-09-01

Regulation of Apoptosis during Flavivirus Infection

by Toru Okamoto, Tatsuya Suzuki, Shinji Kusakabe, Makoto Tokunaga, Junki Hirano, Yuka Miyata, Yoshiharu Matsuura
Published 2017-08-01

How Do Flaviviruses Hijack Host Cell Functions by Phase Separation?

by Akatsuki Saito, Maya Shofa, Hirotaka Ode, Maho Yumiya, Junki Hirano, Toru Okamoto, Shige H. Yoshimura
Published 2021-07-01

In Vitro Model for a Drug Assessment of Cytochrome P450 Family 3 Subfamily A Member 4 Substrates Using Human Induced Pluripotent Stem Cells and Genome Editing Technology

by Sayaka Deguchi, Tomohiro Shintani, Kazuo Harada, Toru Okamoto, Akinori Takemura, Kazumasa Hirata, Kousei Ito, Kazuo Takayama, Hiroyuki Mizuguchi
Published 2021-08-01

The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate Immune Responses

by Michihiro Takahama, Mitsunori Fukuda, Norihiko Ohbayashi, Tatsuya Kozaki, Takuma Misawa, Toru Okamoto, Yoshiharu Matsuura, Shizuo Akira, Tatsuya Saitoh
Published 2017-09-01

Suppression of HBV replication by the expression of nickase- and nuclease dead-Cas9

by Takeshi Kurihara, Takasuke Fukuhara, Chikako Ono, Satomi Yamamoto, Kentaro Uemura, Toru Okamoto, Masaya Sugiyama, Daisuke Motooka, Shota Nakamura, Masato Ikawa, Masashi Mizokami, Yoshihiko Maehara, Yoshiharu Matsuura
Published 2017-07-01

Amphipathic α-helices in apolipoproteins are crucial to the formation of infectious hepatitis C virus particles.

by Takasuke Fukuhara, Masami Wada, Shota Nakamura, Chikako Ono, Mai Shiokawa, Satomi Yamamoto, Takashi Motomura, Toru Okamoto, Daisuke Okuzaki, Masahiro Yamamoto, Izumu Saito, Takaji Wakita, Kazuhiko Koike, Yoshiharu Matsuura
Published 2014-12-01

Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus.

by Satomi Yamamoto, Takasuke Fukuhara, Chikako Ono, Kentaro Uemura, Yukako Kawachi, Mai Shiokawa, Hiroyuki Mori, Masami Wada, Ryoichi Shima, Toru Okamoto, Nobuhiko Hiraga, Ryosuke Suzuki, Kazuaki Chayama, Takaji Wakita, Yoshiharu Matsuura
Published 2016-05-01

Phenotypic Characterization by Single-Cell Mass Cytometry of Human Intrahepatic and Peripheral NK Cells in Patients with Hepatocellular Carcinoma

by Yuichi Yoshida, Sachiyo Yoshio, Taiji Yamazoe, Taizo Mori, Yuriko Tsustui, Hironari Kawai, Shiori Yoshikawa, Takasuke Fukuhara, Toru Okamoto, Yoshihiro Ono, Yu Takahashi, Ryuki Hashida, Takumi Kawaguchi, Akinobu Taketomi, Tatsuya Kanto
Published 2021-06-01

Host-derived apolipoproteins play comparable roles with viral secretory proteins Erns and NS1 in the infectious particle formation of Flaviviridae.

by Takasuke Fukuhara, Tomokazu Tamura, Chikako Ono, Mai Shiokawa, Hiroyuki Mori, Kentaro Uemura, Satomi Yamamoto, Takeshi Kurihara, Toru Okamoto, Ryosuke Suzuki, Kentaro Yoshii, Takeshi Kurosu, Manabu Igarashi, Hiroshi Aoki, Yoshihiro Sakoda, Yoshiharu Matsuura
Published 2017-06-01

Semagacestat Is a Pseudo-Inhibitor of γ-Secretase

by Shinji Tagami, Kanta Yanagida, Takashi S. Kodama, Mako Takami, Naoki Mizuta, Hiroshi Oyama, Kouhei Nishitomi, Yu-wen Chiu, Toru Okamoto, Takeshi Ikeuchi, Gaku Sakaguchi, Takashi Kudo, Yoshiharu Matsuura, Akio Fukumori, Masatoshi Takeda, Yasuo Ihara, Masayasu Okochi
Published 2017-10-01

Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2

by Yusuke Higuchi, Tatsuya Suzuki, Takao Arimori, Nariko Ikemura, Emiko Mihara, Yuhei Kirita, Eriko Ohgitani, Osam Mazda, Daisuke Motooka, Shota Nakamura, Yusuke Sakai, Yumi Itoh, Fuminori Sugihara, Yoshiharu Matsuura, Satoaki Matoba, Toru Okamoto, Junichi Takagi, Atsushi Hoshino
Published 2021-06-01

Infection with flaviviruses requires BCLXL for cell survival.

by Tatsuya Suzuki, Toru Okamoto, Hiroshi Katoh, Yukari Sugiyama, Shinji Kusakabe, Makoto Tokunaga, Junki Hirano, Yuka Miyata, Takasuke Fukuhara, Masahito Ikawa, Takashi Satoh, Sachiyo Yoshio, Ryosuke Suzuki, Masayuki Saijo, David C S Huang, Tatsuya Kanto, Shizuo Akira, Yoshiharu Matsuura
Published 2018-09-01

TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis

by Sayaka Aizawa, Toru Okamoto, Yukari Sugiyama, Takahisa Kouwaki, Ayano Ito, Tatsuya Suzuki, Chikako Ono, Takasuke Fukuhara, Masahiro Yamamoto, Masayasu Okochi, Nobuhiko Hiraga, Michio Imamura, Kazuaki Chayama, Ryosuke Suzuki, Ikuo Shoji, Kohji Moriishi, Kyoji Moriya, Kazuhiko Koike, Yoshiharu Matsuura
Published 2016-05-01

Characterization of miR-122-independent propagation of HCV.

by Chikako Ono, Takasuke Fukuhara, Daisuke Motooka, Shota Nakamura, Daisuke Okuzaki, Satomi Yamamoto, Tomokazu Tamura, Hiroyuki Mori, Asuka Sato, Kentaro Uemura, Yuzy Fauzyah, Takeshi Kurihara, Takahiro Suda, Akira Nishio, Su Su Hmwe, Toru Okamoto, Tomohide Tatsumi, Tetsuo Takehara, Kazuaki Chayama, Takaji Wakita, Kazuhiko Koike, Yoshiharu Matsuura
Published 2017-05-01