NADPH oxidases promote apoptosis by activating ZNRF1 ubiquitin ligase in neurons treated with an exogenously applied oxidant

by Shuji Wakatsuki, Toshiyuki Araki
Published 2016-03-01

Specific phospholipid scramblases are involved in exposure of phosphatidylserine, an “eat-me” signal for phagocytes, on degenerating axons

by Shuji Wakatsuki, Toshiyuki Araki
Published 2017-03-01

Novel Molecular Basis for Synapse Formation: Small Non-coding Vault RNA Functions as a Riboregulator of MEK1 to Modulate Synaptogenesis

by Shuji Wakatsuki, Toshiyuki Araki
Published 2021-09-01

Human vault RNA1-1, but not vault RNA2-1, modulates synaptogenesis

by Shuji Wakatsuki, Moeka Ohno, Toshiyuki Araki
Published 2021-01-01

Axonal Transport and Local Translation of mRNA in Neurodegenerative Diseases

by Seiichi Nagano, Seiichi Nagano, Toshiyuki Araki
Published 2021-06-01

Na+/H+ exchangers induce autophagy in neurons and inhibit polyglutamine-induced aggregate formation.

by Kazuya Togashi, Shuji Wakatsuki, Akiko Furuno, Shinji Tokunaga, Yoshitaka Nagai, Toshiyuki Araki
Published 2013-01-01

Generation of a transgene-free iPSC line and genetically modified line from a facioscapulohumeral muscular dystrophy type 2 (FSHD2) patient with SMCHD1 p.Lys607Ter mutation

by Mitsuru Sasaki-Honda, Akihiro Kagita, Tatsuya Jonouchi, Toshiyuki Araki, Akitsu Hotta, Hidetoshi Sakurai
Published 2020-08-01

Cellular interplay via cytokine hierarchy causes pathological cardiac hypertrophy in RAF1-mutant Noonan syndrome

by Jiani C. Yin, Mathew J. Platt, Xixi Tian, Xue Wu, Peter H. Backx, Jeremy A. Simpson, Toshiyuki Araki, Benjamin G. Neel
Published 2017-05-01

Taxanes and platinum derivatives impair Schwann cells via distinct mechanisms

by Satoshi Imai, Madoka Koyanagi, Ziauddin Azimi, Yui Nakazato, Mayuna Matsumoto, Takashi Ogihara, Atsushi Yonezawa, Tomohiro Omura, Shunsaku Nakagawa, Shuji Wakatsuki, Toshiyuki Araki, Shuji Kaneko, Takayuki Nakagawa, Kazuo Matsubara
Published 2017-07-01

Role of non-macrophage cell-derived HMGB1 in oxaliplatin-induced peripheral neuropathy and its prevention by the thrombin/thrombomodulin system in rodents: negative impact of antic...

by Maho Tsubota, Ryotaro Fukuda, Yusuke Hayashi, Takaya Miyazaki, Shin Ueda, Rika Yamashita, Nene Koike, Fumiko Sekiguchi, Hidenori Wake, Shuji Wakatsuki, Yuka Ujiie, Toshiyuki Araki, Masahiro Nishibori, Atsufumi Kawabata
Published 2019-10-01

The Noonan Syndrome-linked Raf1L613V mutation drives increased glial number in the mouse cortex and enhanced learning.

by Michael C Holter, Lauren T Hewitt, Stephanie V Koebele, Jessica M Judd, Lei Xing, Heather A Bimonte-Nelson, Cheryl D Conrad, Toshiyuki Araki, Benjamin G Neel, William D Snider, Jason M Newbern
Published 2019-04-01

Hepatic rRNA Transcription Regulates High-Fat-Diet-Induced Obesity

by Shohei Oie, Kazuya Matsuzaki, Wataru Yokoyama, Shinji Tokunaga, Tsuyoshi Waku, Song-Iee Han, Naoya Iwasaki, Aya Mikogai, Kayoko Yasuzawa-Tanaka, Hiroyuki Kishimoto, Hiromi Hiyoshi, Yuka Nakajima, Toshiyuki Araki, Keiji Kimura, Junn Yanagisawa, Akiko Murayama
Published 2014-05-01

Brain/MINDS beyond human brain MRI project: A protocol for multi-level harmonization across brain disorders throughout the lifespan

by Shinsuke Koike, Saori C. Tanaka, Tomohisa Okada, Toshihiko Aso, Ayumu Yamashita, Okito Yamashita, Michiko Asano, Norihide Maikusa, Kentaro Morita, Naohiro Okada, Masaki Fukunaga, Akiko Uematsu, Hiroki Togo, Atsushi Miyazaki, Katsutoshi Murata, Yuta Urushibata, Joonas Autio, Takayuki Ose, Junichiro Yoshimoto, Toshiyuki Araki, Matthew F. Glasser, David C. Van Essen, Megumi Maruyama, Norihiro Sadato, Mitsuo Kawato, Kiyoto Kasai, Yasumasa Okamoto, Takashi Hanakawa, Takuya Hayashi
Published 2021-01-01

NAD+ Repletion Rescues Female Fertility during Reproductive Aging

by Michael J. Bertoldo, Dave R. Listijono, Wing-Hong Jonathan Ho, Angelique H. Riepsamen, Dale M. Goss, Dulama Richani, Xing L. Jin, Saabah Mahbub, Jared M. Campbell, Abbas Habibalahi, Wei-Guo Nicholas Loh, Neil A. Youngson, Jayanthi Maniam, Ashley S.A. Wong, Kaisa Selesniemi, Sonia Bustamante, Catherine Li, Yiqing Zhao, Maria B. Marinova, Lynn-Jee Kim, Laurin Lau, Rachael M. Wu, A. Stefanie Mikolaizak, Toshiyuki Araki, David G. Le Couteur, Nigel Turner, Margaret J. Morris, Kirsty A. Walters, Ewa Goldys, Christopher O’Neill, Robert B. Gilchrist, David A. Sinclair, Hayden A. Homer, Lindsay E. Wu
Published 2020-02-01