Bacterial fitness landscapes stratify based on proteome allocation associated with discrete aero-types.

by Ke Chen, Amitesh Anand, Connor Olson, Troy E Sandberg, Ye Gao, Nathan Mih, Bernhard O Palsson
Published 2021-01-01

Evolution of E. coli on [U-13C]Glucose Reveals a Negligible Isotopic Influence on Metabolism and Physiology.

by Troy E Sandberg, Christopher P Long, Jacqueline E Gonzalez, Adam M Feist, Maciek R Antoniewicz, Bernhard O Palsson
Published 2016-01-01

Evolution of gene knockout strains of E. coli reveal regulatory architectures governed by metabolism

by Douglas McCloskey, Sibei Xu, Troy E. Sandberg, Elizabeth Brunk, Ying Hefner, Richard Szubin, Adam M. Feist, Bernhard O. Palsson
Published 2018-09-01

Causal mutations from adaptive laboratory evolution are outlined by multiple scales of genome annotations and condition-specificity

by Patrick V. Phaneuf, James T. Yurkovich, David Heckmann, Muyao Wu, Troy E. Sandberg, Zachary A. King, Justin Tan, Bernhard O. Palsson, Adam M. Feist
Published 2020-07-01

Laboratory evolution reveals a two-dimensional rate-yield tradeoff in microbial metabolism.

by Chuankai Cheng, Edward J O'Brien, Douglas McCloskey, Jose Utrilla, Connor Olson, Ryan A LaCroix, Troy E Sandberg, Adam M Feist, Bernhard O Palsson, Zachary A King
Published 2019-06-01

Growth Adaptation of gnd and sdhCB Escherichia coli Deletion Strains Diverges From a Similar Initial Perturbation of the Transcriptome

by Douglas McCloskey, Douglas McCloskey, Sibei Xu, Troy E. Sandberg, Elizabeth Brunk, Ying Hefner, Richard Szubin, Adam M. Feist, Adam M. Feist, Bernhard O. Palsson, Bernhard O. Palsson
Published 2018-08-01

Enzyme promiscuity shapes adaptation to novel growth substrates

by Gabriela I Guzmán, Troy E Sandberg, Ryan A LaCroix, Ákos Nyerges, Henrietta Papp, Markus de Raad, Zachary A King, Ying Hefner, Trent R Northen, Richard A Notebaart, Csaba Pál, Bernhard O Palsson, Balázs Papp, Adam M Feist
Published 2019-04-01

The genetic basis for adaptation of model-designed syntrophic co-cultures.

by Colton J Lloyd, Zachary A King, Troy E Sandberg, Ying Hefner, Connor A Olson, Patrick V Phaneuf, Edward J O'Brien, Jon G Sanders, Rodolfo A Salido, Karenina Sanders, Caitriona Brennan, Gregory Humphrey, Rob Knight, Adam M Feist
Published 2019-03-01