Clonal Dominance With Retroviral Vector Insertions Near the ANGPT1 and ANGPT2 Genes in a Human Xenotransplant Mouse Model

by Reinhard Haemmerle, Ruhi Phaltane, Michael Rothe, Simon Schröder, Axel Schambach, Thomas Moritz, Ute Modlich
Published 2014-01-01

Inhibition of Thrombopoietin/Mpl Signaling in Adult Hematopoiesis Identifies New Candidates for Hematopoietic Stem Cell Maintenance.

by Saskia Kohlscheen, Sabine Wintterle, Adrian Schwarzer, Christel Kamp, Martijn H Brugman, Daniel C Breuer, Guntram Büsche, Christopher Baum, Ute Modlich
Published 2015-01-01

Engineering Next-Generation BET-Independent MLV Vectors for Safer Gene Therapy

by Sara El Ashkar, Dominique Van Looveren, Franziska Schenk, Lenard S. Vranckx, Jonas Demeulemeester, Jan De Rijck, Zeger Debyser, Ute Modlich, Rik Gijsbers
Published 2017-06-01

Hematopoietic Stem Cell Transplantation Restores Naïve T-Cell Populations in Atm-Deficient Mice and in Preemptively Treated Patients With Ataxia-Telangiectasia

by Ruth Duecker, Patrick C. Baer, Aileen Buecker, Sabine Huenecke, Lisa-Marie Pfeffermann, Ute Modlich, Shahrzad Bakhtiar, Peter Bader, Stefan Zielen, Ralf Schubert
Published 2019-11-01

Forming megakaryocytes from murine induced pluripotent stem cells by the inducible overexpression of supporting factors

by Katharina Cullmann, Magdalena Jahn, Markus Spindler, Franziska Schenk, Georgi Manukjan, Adele Mucci, Doris Steinemann, Klaus Boller, Harald Schulze, Markus Bender, Thomas Moritz, Ute Modlich
Published 2021-01-01

In vivo generation of human CD19‐CAR T cells results in B‐cell depletion and signs of cytokine release syndrome

by Anett Pfeiffer, Frederic B Thalheimer, Sylvia Hartmann, Annika M Frank, Ruben R Bender, Simon Danisch, Caroline Costa, Winfried S Wels, Ute Modlich, Renata Stripecke, Els Verhoeyen, Christian J Buchholz
Published 2018-11-01

High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia

by Stephan Müller, Stephan Müller, Tobias Bexte, Tobias Bexte, Tobias Bexte, Veronika Gebel, Veronika Gebel, Franziska Kalensee, Franziska Kalensee, Eva Stolzenberg, Eva Stolzenberg, Jessica Hartmann, Ulrike Koehl, Ulrike Koehl, Ulrike Koehl, Axel Schambach, Axel Schambach, Winfried S. Wels, Winfried S. Wels, Winfried S. Wels, Ute Modlich, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich
Published 2020-01-01

A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis

by Sebastian Dütting, Frederique Gaits-Iacovoni, David Stegner, Michael Popp, Adrien Antkowiak, Judith M.M. van Eeuwijk, Paquita Nurden, Simon Stritt, Tobias Heib, Katja Aurbach, Oguzhan Angay, Deya Cherpokova, Niels Heinz, Ayesha A. Baig, Maximilian G. Gorelashvili, Frank Gerner, Katrin G. Heinze, Jerry Ware, Georg Krohne, Zaverio M. Ruggeri, Alan T. Nurden, Harald Schulze, Ute Modlich, Irina Pleines, Cord Brakebusch, Bernhard Nieswandt
Published 2017-06-01