Reengineering anthrax toxin protective antigen for improved receptor-specific protein delivery

by Lukas Becker, Wouter P. R. Verdurmen, Andreas Plückthun
Published 2020-08-01

Thermodynamic Stability Is a Strong Predictor for the Delivery of DARPins to the Cytosol via Anthrax Toxin

by Lukas Becker, Jasleen Singh Badwal, Fabian Brandl, Wouter P. R. Verdurmen, Andreas Plückthun
Published 2021-08-01

Metabolic Switching of Tumor Cells under Hypoxic Conditions in a Tumor-on-a-chip Model

by Valentina Palacio-Castañeda, Lucas Kooijman, Bastien Venzac, Wouter P.R. Verdurmen, Séverine Le Gac
Published 2020-04-01

A Computational Investigation of In Vivo Cytosolic Protein Delivery for Cancer Therapy

by Camilo Torres, Simon Dumas, Valentina Palacio-Castañeda, Stéphanie Descroix, Roland Brock, Wouter P. R. Verdurmen
Published 2021-04-01

A Hybrid In Silico and Tumor-on-a-Chip Approach to Model Targeted Protein Behavior in 3D Microenvironments

by Valentina Palacio-Castañeda, Simon Dumas, Philipp Albrecht, Thijmen J. Wijgers, Stéphanie Descroix, Wouter P. R. Verdurmen
Published 2021-05-01

Intermolecular biparatopic trapping of ErbB2 prevents compensatory activation of PI3K/AKT via RAS–p110 crosstalk

by Rastislav Tamaskovic, Martin Schwill, Gabriela Nagy-Davidescu, Christian Jost, Dagmar C. Schaefer, Wouter P. R. Verdurmen, Jonas V. Schaefer, Annemarie Honegger, Andreas Plückthun
Published 2016-06-01

Structure analysis and conformational transitions of the cell penetrating peptide transportan 10 in the membrane-bound state.

by Susanne Fanghänel, Parvesh Wadhwani, Erik Strandberg, Wouter P R Verdurmen, Jochen Bürck, Sebastian Ehni, Pavel K Mykhailiuk, Sergii Afonin, Dagmar Gerthsen, Igor V Komarov, Roland Brock, Anne S Ulrich
Published 2014-01-01

Enhanced cellular uptake of albumin-based lyophilisomes when functionalized with cell-penetrating peptide TAT in HeLa cells.

by Etienne van Bracht, Luuk R M Versteegden, Sarah Stolle, Wouter P R Verdurmen, Rob Woestenenk, René Raavé, Theo Hafmans, Egbert Oosterwijk, Roland Brock, Toin H van Kuppevelt, Willeke F Daamen
Published 2014-01-01

EpCAM-Binding DARPins for Targeted Photodynamic Therapy of Ovarian Cancer

by Dirk van den Brand, Sanne A. M. van Lith, Jelske M. de Jong, Mark A. J. Gorris, Valentina Palacio-Castañeda, Stijn T. Couwenbergh, Mark R. G. Goldman, Inge Ebisch, Leon F. Massuger, William P. J. Leenders, Roland Brock, Wouter P. R. Verdurmen
Published 2020-07-01