Plasticity of Intestinal Epithelium: Stem Cell Niches and Regulatory Signals

by Ken Kurokawa, Yoku Hayakawa, Kazuhiko Koike
Published 2021-12-01

Role of Muscarinic Acetylcholine Signaling in Gastrointestinal Cancers

by Mitsuru Konishi, Yoku Hayakawa, Kazuhiko Koike
Published 2019-08-01

Metaplasia in the Stomach—Precursor of Gastric Cancer?

by Hiroto Kinoshita, Yoku Hayakawa, Kazuhiko Koike
Published 2017-09-01

Gastric Stem Cell and Cellular Origin of Cancer

by Masahiro Hata, Yoku Hayakawa, Kazuhiko Koike
Published 2018-10-01

The Origins of Gastric Cancer From Gastric Stem Cells: Lessons From Mouse ModelsSummary

by Yoku Hayakawa, James G. Fox, Timothy C. Wang
Published 2017-05-01

Distinct Features of Autoimmune Gastritis in Patients with Open-Type Chronic Gastritis in Japan

by Mayo Tsuboi, Ryota Niikura, Yoku Hayakawa, Yoshihiro Hirata, Tetsuo Ushiku, Kazuhiko Koike
Published 2020-10-01

Effect of aspirin use on gastric cancer incidence and survival: A systematic review and meta‐analysis

by Ryota Niikura, Yoshihiro Hirata, Yoku Hayakawa, Takuya Kawahara, Atsuo Yamada, Kazuhiko Koike
Published 2020-04-01

Isthmus Stem Cells Are the Origins of Metaplasia in the Gastric Corpus

by Yoku Hayakawa MD,, PhD, James G. Fox DVM,, PhD, Timothy C. Wang, MD
Published 2017-07-01

Mouse Models of Gastric Cancer

by Timothy C. Wang, Sureshkumar Muthupalani, Daniel L. Worthley, Tamas Gonda, James G. Fox, Yoku Hayakawa
Published 2013-01-01

Efficacy of triple therapy with esomeprazole, amoxicillin, and sitafloxacin as a third-line Helicobacter pylori eradication regimen

by Yoshihiro Hirata, Takako Serizawa, Satoki Shichijo, Nobumi Suzuki, Kosuke Sakitani, Yoku Hayakawa, Atsuo Yamada, Kazuhiko Koike
Published 2016-10-01

The Reduction in Gastric Atrophy after <i>Helicobacter pylori</i> Eradication Is Reduced by Treatment with Inhibitors of Gastric Acid Secretion

by Ryota Niikura, Yoku Hayakawa, Yoshihiro Hirata, Keiji Ogura, Mitsuhiro Fujishiro, Atsuo Yamada, Tetsuo Ushiku, Mitsuru Konishi, Masashi Fukayama, Kazuhiko Koike
Published 2019-04-01

Prevalence of pks-positive Escherichia coli in Japanese patients with or without colorectal cancer

by Takayuki Shimpoh, Yoshihiro Hirata, Sozaburo Ihara, Nobumi Suzuki, Hiroto Kinoshita, Yoku Hayakawa, Yumiko Ota, Akiko Narita, Shuntaro Yoshida, Atsuo Yamada, Kazuhiko Koike
Published 2017-06-01

Hypergastrinemia Expands Gastric ECL Cells Through CCK2R+ Progenitor Cells via ERK ActivationSummary

by Weiwei Sheng, Ermanno Malagola, Henrik Nienhüser, Zhengyu Zhang, Woosook Kim, Leah Zamechek, Antonia Sepulveda, Masahiro Hata, Yoku Hayakawa, Chun-Mei Zhao, Duan Chen, Timothy C. Wang
Published 2020-01-01

Interleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesis.

by Hiroto Kinoshita, Yoshihiro Hirata, Hayato Nakagawa, Kei Sakamoto, Yoku Hayakawa, Ryota Takahashi, Wachiko Nakata, Kosuke Sakitani, Takako Serizawa, Yohko Hikiba, Masao Akanuma, Wataru Shibata, Shin Maeda, Kazuhiko Koike
Published 2013-01-01

Colonoscopy reduces colorectal cancer mortality: A multicenter, long-term, colonoscopy-based cohort study.

by Ryota Niikura, Yoshihiro Hirata, Nobumi Suzuki, Atsuo Yamada, Yoku Hayakawa, Hirobumi Suzuki, Shinzo Yamamoto, Ryo Nakata, Junko Komatsu, Makoto Okamoto, Makoto Kodaira, Tomohiro Shinozaki, Mitsuhiro Fujishiro, Toshiaki Watanabe, Kazuhiko Koike
Published 2017-01-01

Cell fate analysis of zone 3 hepatocytes in liver injury and tumorigenesis

by Shigeyuki Kurosaki, Hayato Nakagawa, Yuki Hayata, Satoshi Kawamura, Yuki Matsushita, Tomoharu Yamada, Koji Uchino, Yoku Hayakawa, Nobumi Suzuki, Masahiro Hata, Mayo Tsuboi, Hiroto Kinoshita, Yasuo Tanaka, Takuma Nakatsuka, Yoshihiro Hirata, Keisuke Tateishi, Kazuhiko Koike
Published 2021-08-01

Nonsteroidal anti‐inflammatory drugs prevent gastric cancer associated with the use of proton pump inhibitors after Helicobacter pylori eradication

by Junya Arai, Ryota Niikura, Yoku Hayakawa, Hiroki Sato, Takuya Kawahara, Tetsuro Honda, Kenkei Hasatani, Naohiro Yoshida, Tsutomu Nishida, Tetsuya Sumiyoshi, Shu Kiyotoki, Takashi Ikeya, Masahiro Arai, Nobumi Suzuki, Yosuke Tsuji, Atsuo Yamada, Kazuhiko Koike
Published 2021-07-01

Use of Antibiotics and Probiotics Reduces the Risk of Metachronous Gastric Cancer after Endoscopic Resection

by Junya Arai, Ryota Niikura, Yoku Hayakawa, Takuya Kawahara, Tetsuro Honda, Kenkei Hasatani, Naohiro Yoshida, Tsutomu Nishida, Tetsuya Sumiyoshi, Shu Kiyotoki, Takashi Ikeya, Masahiro Arai, Nobumi Suzuki, Yosuke Tsuji, Atsuo Yamada, Takashi Kawai, Kazuhiko Koike
Published 2021-05-01

Prox1-positive cells monitor and sustain the murine intestinal epithelial cholinergic niche

by Moritz Middelhoff, Henrik Nienhüser, Giovanni Valenti, H. Carlo Maurer, Yoku Hayakawa, Ryota Takahashi, Woosook Kim, Zhengyu Jiang, Ermanno Malagola, Krystle Cuti, Yagnesh Tailor, Leah B. Zamechek, Bernhard W. Renz, Michael Quante, Kelley S. Yan, Timothy C. Wang
Published 2020-01-01

Delineating proinflammatory microenvironmental signals by ex vivo modeling of the immature intestinal stroma

by Mari Ichinose, Nobumi Suzuki, Tongtong Wang, Josephine A. Wright, Tamsin R. M. Lannagan, Laura Vrbanac, Hiroki Kobayashi, Krystyna Gieniec, Jia Q. Ng, Souzaburo Ihara, Chris Mavrangelos, Yoku Hayakawa, Patrick Hughes, Daniel L. Worthley, Susan L. Woods
Published 2021-03-01