Crystal Structures of TbCatB and rhodesain, potential chemotherapeutic targets and major cysteine proteases of Trypanosoma brucei.

by Iain D Kerr, Peng Wu, Rachael Marion-Tsukamaki, Zachary B Mackey, Linda S Brinen
Published 2010-06-01

RNA interference of Trypanosoma brucei cathepsin B and L affects disease progression in a mouse model.

by Maha-Hamadien Abdulla, Theresa O'Brien, Zachary B Mackey, Mohamed Sajid, Dennis J Grab, James H McKerrow
Published 2008-09-01

Early invasion of brain parenchyma by African trypanosomes.

by Ute Frevert, Alexandru Movila, Olga V Nikolskaia, Jayne Raper, Zachary B Mackey, Maha Abdulla, James McKerrow, Dennis J Grab
Published 2012-01-01

Trypanosoma cruzi CYP51 inhibitor derived from a Mycobacterium tuberculosis screen hit.

by Chiung-Kuang Chen, Patricia S Doyle, Liudmila V Yermalitskaya, Zachary B Mackey, Kenny K H Ang, James H McKerrow, Larissa M Podust
Published 2009-01-01

Mining a cathepsin inhibitor library for new antiparasitic drug leads.

by Kenny K H Ang, Joseline Ratnam, Jiri Gut, Jennifer Legac, Elizabeth Hansell, Zachary B Mackey, Katarzyna M Skrzypczynska, Anjan Debnath, Juan C Engel, Philip J Rosenthal, James H McKerrow, Michelle R Arkin, Adam R Renslo
Published 2011-01-01