Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia

Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia

Abstract Background Although the etiology of chronic lymphocytic leukemia (CLL), the most common type of adult leukemia, is still unclear, strong evidence implicates antigen involvement in disease ontogeny and evolution. Primary and 3D structure analysis has been utilised in order to discover indica...

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Main Authors: Eleftheria Polychronidou, Ilias Kalamaras, Andreas Agathangelidis, Lesley-Ann Sutton, Xiao-Jie Yan, Vasilis Bikos, Anna Vardi, Konstantinos Mochament, Nicholas Chiorazzi, Chrysoula Belessi, Richard Rosenquist, Paolo Ghia, Kostas Stamatopoulos, Panayiotis Vlamos, Anna Chailyan, Nanna Overby, Paolo Marcatili, Anastasia Hatzidimitriou, Dimitrios Tzovaras
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Bioinformatics
Subjects:
CLL protein clustering
3D protein descriptors
descriptor fusion
Online Access:http://link.springer.com/article/10.1186/s12859-018-2381-1

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http://link.springer.com/article/10.1186/s12859-018-2381-1

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