LPS-induced lung inflammation in marmoset monkeys - an acute model for anti-inflammatory drug testing.

Increasing incidence and substantial morbidity and mortality of respiratory diseases requires the development of new human-specific anti-inflammatory and disease-modifying therapeutics. Therefore, new predictive animal models that closely reflect human lung pathology are needed. In the current study...

Full description

Bibliographic Details
Main Authors: Sophie Seehase, Hans-Dieter Lauenstein, Christina Schlumbohm, Simone Switalla, Vanessa Neuhaus, Christine Förster, Hans-Gerd Fieguth, Olaf Pfennig, Eberhard Fuchs, Franz-Josef Kaup, Martina Bleyer, Jens M Hohlfeld, Armin Braun, Katherina Sewald, Sascha Knauf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3429492?pdf=render