Epigenetic signatures in cancer: proper controls, current challenges and the potential for clinical translation
Abstract Epigenetic alterations are associated with normal biological processes such as aging or differentiation. Changes in global epigenetic signatures, together with genetic alterations, are driving events in several diseases including cancer. Comparative studies of cancer and healthy tissues fou...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-02-01
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Series: | Genome Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13073-021-00837-7 |