Case Report: Pseudomeningeosis and Demyelinating Metastasis-Like Lesions From Checkpoint Inhibitor Therapy in Malignant Melanoma

Case Report: Pseudomeningeosis and Demyelinating Metastasis-Like Lesions From Checkpoint Inhibitor Therapy in Malignant Melanoma

Immune checkpoint inhibitors (ICIs) have considerably expanded the effective treatment options for malignant melanoma. ICIs revert tumor-associated immunosuppression and potentiate T-cell mediated tumor clearance. Immune-related neurologic adverse events (irNAEs) manifest in the central (CNS) or per...

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Bibliographic Details
Main Authors: Teresa Schmidt, Sied Kebir, Elisabeth Livingstone, Andreas Junker, Stefan Zülow, Lazaros Lazaridis, Christoph Oster, Eleftheria Chorti, Daniela Pierscianek, Refik Pul, Kathy Keyvani, Ulrich Sure, Martin Stuschke, Christoph Kleinschnitz, Björn Scheffler, Lisa Zimmer, Martin Glas
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
melanoma
immune checkpoint inhibitors
immune-related adverse events
leptomeningeal metastasis
pseudomeningeosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.637185/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.637185/full

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