Towards a “Sample-In, Answer-Out” Point-of-Care Platform for Nucleic Acid Extraction and Amplification: Using an HPV E6/E7 mRNA Model System

Towards a “Sample-In, Answer-Out” Point-of-Care Platform for Nucleic Acid Extraction and Amplification: Using an HPV E6/E7 mRNA Model System

The paper presents the development of a “proof-of-principle” hands-free and self-contained diagnostic platform for detection of human papillomavirus (HPV) E6/E7 mRNA in clinical specimens. The automated platform performs chip-based sample preconcentration, nucleic acid extraction, amplification, and...

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Bibliographic Details
Main Authors: Anja Gulliksen, Helen Keegan, Cara Martin, John O'Leary, Lars A. Solli, Inger Marie Falang, Petter Grønn, Aina Karlgård, Michal M. Mielnik, Ib-Rune Johansen, Terje R. Tofteberg, Tobias Baier, Rainer Gransee, Klaus Drese, Thomas Hansen-Hagge, Lutz Riegger, Peter Koltay, Roland Zengerle, Frank Karlsen, Dag Ausen, Liv Furuberg
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2012/905024

Internet

http://dx.doi.org/10.1155/2012/905024

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