Systemic down-regulation of delta-9 desaturase promotes muscle oxidative metabolism and accelerates muscle function recovery following nerve injury.

Systemic down-regulation of delta-9 desaturase promotes muscle oxidative metabolism and accelerates muscle function recovery following nerve injury.

The progressive deterioration of the neuromuscular axis is typically observed in degenerative conditions of the lower motor neurons, such as amyotrophic lateral sclerosis (ALS). Neurodegeneration in this disease is associated with systemic metabolic perturbations, including hypermetabolism and dysli...

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Bibliographic Details
Main Authors: Ghulam Hussain, Florent Schmitt, Alexandre Henriques, Thiebault Lequeu, Frederique Rene, Françoise Bindler, Sylvie Dirrig-Grosch, Hugues Oudart, Lavinia Palamiuc, Marie-Helene Metz-Boutigue, Luc Dupuis, Eric Marchioni, Jose-Luis Gonzalez De Aguilar, Jean-Philippe Loeffler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3681796?pdf=render

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http://europepmc.org/articles/PMC3681796?pdf=render

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