In Vivo Tau Imaging for a Diagnostic Platform of Tauopathy Using the rTg4510 Mouse Line

In Vivo Tau Imaging for a Diagnostic Platform of Tauopathy Using the rTg4510 Mouse Line

Association of tau deposition with neurodegeneration in Alzheimer’s disease (AD) and related tau-positive neurological disorders collectively referred to as tauopathies indicates contribution of tau aggregates to neurotoxicity. The discovery of tau gene mutations in FTDP-17-tau kindreds has provided...

Full description

Bibliographic Details
Main Authors: Naruhiko Sahara, Masafumi Shimojo, Maiko Ono, Hiroyuki Takuwa, Marcelo Febo, Makoto Higuchi, Tetsuya Suhara
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Neurology
Subjects:
tau protein
transgenic mouse
positron emission tomography
magnetic resonance imaging
two-photon microscopy
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00663/full

Internet

http://journal.frontiersin.org/article/10.3389/fneur.2017.00663/full

Similar Items