Allele-Selective Transcriptome Recruitment to Polysomes Primed for Translation: Protein-Coding and Noncoding RNAs, and RNA Isoforms.

Allele-Selective Transcriptome Recruitment to Polysomes Primed for Translation: Protein-Coding and Noncoding RNAs, and RNA Isoforms.

mRNA translation into proteins is highly regulated, but the role of mRNA isoforms, noncoding RNAs (ncRNAs), and genetic variants remains poorly understood. mRNA levels on polysomes have been shown to correlate well with expressed protein levels, pointing to polysomal loading as a critical factor. To...

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Bibliographic Details
Main Authors: Roshan Mascarenhas, Maciej Pietrzak, Ryan M Smith, Amy Webb, Danxin Wang, Audrey C Papp, Julia K Pinsonneault, Michal Seweryn, Grzegorz Rempala, Wolfgang Sadee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4558023?pdf=render

Internet

http://europepmc.org/articles/PMC4558023?pdf=render

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