GSK-3β/NFAT Signaling Is Involved in Testosterone-Induced Cardiac Myocyte Hypertrophy.

Testosterone induces cardiac hypertrophy through a mechanism that involves a concerted crosstalk between cytosolic and nuclear signaling pathways. Nuclear factor of activated T-cells (NFAT) is associated with the promotion of cardiac hypertrophy, glycogen synthase kinase-3β (GSK-3β) is considered to...

Full description

Bibliographic Details
Main Authors: Javier Duran, Cesar Oyarce, Mario Pavez, Denisse Valladares, Carla Basualto-Alarcon, Daniel Lagos, Genaro Barrientos, Mayarling Francisca Troncoso, Cristian Ibarra, Manuel Estrada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5158037?pdf=render