LRGUK-1 is required for basal body and manchette function during spermatogenesis and male fertility.

Male infertility affects at least 5% of reproductive age males. The most common pathology is a complex presentation of decreased sperm output and abnormal sperm shape and motility referred to as oligoasthenoteratospermia (OAT). For the majority of OAT men a precise diagnosis cannot be provided. Here...

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Bibliographic Details
Main Authors: Yan Liu, Kathleen DeBoer, David M de Kretser, Liza O'Donnell, Anne E O'Connor, D Jo Merriner, Hidenobu Okuda, Belinda Whittle, David A Jans, Athina Efthymiadis, Robert I McLachlan, Christopher J Ormandy, Chris C Goodnow, Duangporn Jamsai, Moira K O'Bryan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4363142?pdf=render