Pediatric cancer gone viral. Part I: strategies for utilizing oncolytic herpes simplex virus-1 in children

Progress for improving outcomes in pediatric patients with solid tumors remains slow. In addition, currently available therapies are fraught with numerous side effects, often causing significant life-long morbidity for long-term survivors. The use of viruses to kill tumor cells based on their increa...

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Bibliographic Details
Main Authors: Timothy P Cripe, Chun-Yu Chen, Nicholas L Denton, Kellie B Haworth, Brian Hutzen, Jennifer L Leddon, Keri A Streby, Pin-Yi Wang, James M Markert, Alicia M Waters, George Yancey Gillespie, Elizabeth A Beierle, Gregory K Friedman
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770516300171