The impact of nitration on the structure and immunogenicity of the major birch pollen allergen Bet v 1.0101.

Allergy prevalence has increased in industrialized countries. One contributing factor could be pollution, which can cause nitration of allergens exogenously (in the air) or endogenously (in inflamed lung tissue). We investigated the impact of nitration on both the structural and immunological behavi...

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Main Authors: Chloé Ackaert, Stefan Kofler, Jutta Horejs-Hoeck, Nora Zulehner, Claudia Asam, Susanne von Grafenstein, Julian E Fuchs, Peter Briza, Klaus R Liedl, Barbara Bohle, Fátima Ferreira, Hans Brandstetter, Gertie J Oostingh, Albert Duschl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25126882/pdf/?tool=EBI