Oxidative Stress in Dilated Cardiomyopathy Caused by MYBPC3 Mutation

Cardiomyopathies can result from mutations in genes encoding sarcomere proteins including MYBPC3, which encodes cardiac myosin binding protein-C (cMyBP-C). However, whether oxidative stress is augmented due to contractile dysfunction and cardiomyocyte damage in MYBPC3-mutated cardiomyopathies has no...

Full description

Bibliographic Details
Main Authors: Thomas L. Lynch, Mayandi Sivaguru, Murugesan Velayutham, Arturo J. Cardounel, Michelle Michels, David Barefield, Suresh Govindan, Cristobal dos Remedios, Jolanda van der Velden, Sakthivel Sadayappan
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2015/424751