Genomic predictors for recurrence patterns of hepatocellular carcinoma: model derivation and validation.

BACKGROUND: Typically observed at 2 y after surgical resection, late recurrence is a major challenge in the management of hepatocellular carcinoma (HCC). We aimed to develop a genomic predictor that can identify patients at high risk for late recurrence and assess its clinical implications. METHODS...

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Main Authors: Ji Hoon Kim, Bo Hwa Sohn, Hyun-Sung Lee, Sang-Bae Kim, Jeong Eun Yoo, Yun-Yong Park, Woojin Jeong, Sung Sook Lee, Eun Sung Park, Ahmed Kaseb, Baek Hui Kim, Wan Bae Kim, Jong Eun Yeon, Kwan Soo Byun, In-Sun Chu, Sung Soo Kim, Xin Wei Wang, Snorri S Thorgeirsson, John M Luk, Koo Jeong Kang, Jeonghoon Heo, Young Nyun Park, Ju-Seog Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC4275163?pdf=render