Cross-serotype immunity induced by immunization with a conserved rhinovirus capsid protein.

Human rhinovirus (RV) infections are the principle cause of common colds and precipitate asthma and COPD exacerbations. There is currently no RV vaccine, largely due to the existence of ∼150 strains. We aimed to define highly conserved areas of the RV proteome and test their usefulness as candidate...

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Bibliographic Details
Main Authors: Nicholas Glanville, Gary R McLean, Bruno Guy, Valerie Lecouturier, Catherine Berry, Yves Girerd, Christophe Gregoire, Ross P Walton, Rebecca M Pearson, Tatiana Kebadze, Nicolas Burdin, Nathan W Bartlett, Jeffrey W Almond, Sebastian L Johnston
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3784482?pdf=render