Breaking the mold: transcription factors in the anucleate platelet and platelet-derived microparticles

Breaking the mold: transcription factors in the anucleate platelet and platelet-derived microparticles

Platelets are small anucleate blood cells derived from megakaryocytes. In addition to their pivotal roles in hemostasis, platelets are the smallest, yet most abundant, immune cell and regulate inflammation, immunity, and disease progression. Although platelets lack DNA, and thus no functional transc...

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Bibliographic Details
Main Authors: Katie L Lannan, Julie eSahler, Nina eKim, Sherry L Spinelli, Sanjay B Maggirwar, Olivier eGARRAUD, Fabrice eCOGNASSE, Neil eBlumberg, Richard P Phipps
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Immunology
Subjects:
PPAR alpha
PPAR gamma
Transcription Factors
microparticles
platelets
NFkappab
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00048/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00048/full

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