Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing

Adaptive immunity from both B and T cells critically controls the rejection or survival of transplanted organs. Here the authors show, by analyzing human B cell receptor repertoire in longitudinal studies of patients receiving kidney transplants, that repertoire diversity is positively associated wi...

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Bibliographic Details
Main Authors: Silvia Pineda, Tara K. Sigdel, Juliane M. Liberto, Flavio Vincenti, Marina Sirota, Minnie M. Sarwal
Format: Article
Language:English
Published: Nature Publishing Group 2019-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09930-3