SIRT1, Is It a Tumor Promoter or Tumor Suppressor?

<p>SIRT1 has been considered as a tumor promoter because of its increased expression in some types of cancers and its role in inactivating proteins that are involved in tumor suppression and DNA damage repair. However, recent studies demonstrated that SIRT1 levels are reduced in some other typ...

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Bibliographic Details
Main Author: Chu-Xia Deng
Format: Article
Language:English
Published: Ivyspring International Publisher 2009-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v05p0147.htm