In silico analysis of glycinamide ribonucleotide transformylase inhibition by PY873, PY899 and DIA
In humans, purine de novo synthesis pathway consists of multi-functional enzymes. Nucleotide metabolism enzymes are potential drug targets for treating cancer and autoimmune diseases. Glycinamide ribonucleotide transformylase (GART) is one of the most important trifunctional enzymes involved in puri...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-09-01
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| Series: | Saudi Journal of Biological Sciences |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1319562X14001454 |