In silico analysis of glycinamide ribonucleotide transformylase inhibition by PY873, PY899 and DIA
In humans, purine de novo synthesis pathway consists of multi-functional enzymes. Nucleotide metabolism enzymes are potential drug targets for treating cancer and autoimmune diseases. Glycinamide ribonucleotide transformylase (GART) is one of the most important trifunctional enzymes involved in puri...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-09-01
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Series: | Saudi Journal of Biological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1319562X14001454 |