In silico analysis of glycinamide ribonucleotide transformylase inhibition by PY873, PY899 and DIA

In humans, purine de novo synthesis pathway consists of multi-functional enzymes. Nucleotide metabolism enzymes are potential drug targets for treating cancer and autoimmune diseases. Glycinamide ribonucleotide transformylase (GART) is one of the most important trifunctional enzymes involved in puri...

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Bibliographic Details
Main Authors: Sidra Batool, Muhammad Sulaman Nawaz, Gohar Mushtaq, Fahed Parvaiz, Mohammad A. Kamal
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Saudi Journal of Biological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X14001454

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